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Timolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.
Mixtures: DORZOLOL® UD, GANFORT® UD SOLUCION OFTALMICACategories: Beta Blocking Agents, Non-Selective, Beta Blocking Agents, Non-Selective, and ThiazidesCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.
Synonyms: Recombinant factor IX, Factor IX (Recombinant)Products: OCTANINE® F 500 UI, OCTANINE F ® 250 UINeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approvedcaused by medical procedures in the ear. … [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its pharmacological action by binding to bacterial ribosomes and inhibiting protein synthesis, which is
Mixtures: FAK Care4 Bus and School Yellow ORM D, FAK Care4 Bus and School Yellow ORM DCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexSaquinavir
go.drugbank.com/drugs/DB01232ApprovedInvestigationalIn 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a relatively benign adverse effect profile as compared … [A214382] While its efficacy was initially limited by exceptionally poor oral bioavailability (approximately 4%),[L3450] its current indications require the co-administration of ritonavir - a potent enzyme
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: Invirase - Cap 200mg, BIOQUINAVIR ® CAPSULAS 200MGStavudine
go.drugbank.com/drugs/DB00649ApprovedInvestigationalA dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Synonyms: 2',3'-Didehydro-3'-deoxythimidine, 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymineInternational brands: Ai Fu Ding, Mai Si TingCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalThe prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. … Cetirizine, also commonly known as _Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal
Mixtures: Allergy and Congestion Relief D Original Prescription Strength, VERACETAM NF CAPSULASCategories: Histamine H1 Antagonists, Non-Sedating, P-glycoprotein inhibitorsSimoctocog alfa
go.drugbank.com/drugs/DB09108ApprovedAs patients with haemophilia A are predisposed to episodes of recurrent bleeding [L1115], simoctocog alfa can be administered for the treatment or prevention of bleeding such as prior to surgical procedures … The harvested product is concentrated and purified by a series of chromatography steps.
Products: NUWIQ 500 UI, NUWIQ 2000 UIHuman thrombin
go.drugbank.com/drugs/DB11571ApprovedInvestigationalThrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. … Furthermore, human thrombin is manufactured by chromatographic purification of prothrombin from cryo-poor plasma followed by activation with calcium chloride [FDA Label].
Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml, EVICEL® SELLANTE DE FIBRINA HUMANAProducts: THROMBIRAAS1000 UIMoroctocog alfa
go.drugbank.com/drugs/DB13999ApprovedMoroctocog alfa is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain, which has no known biological function. … Bleeding can range in severity from minor concerns, such as nosebleeds, to more serious events such as hemorrhaging in the joints, brain, or digestive tract [A32280].
Synonyms: B-domain deleted recombinant factor VIII, Human factor VIII, recombinant B-domain deletedProducts: XYNTHA® 2000 UI, XYNTHA® 250 UI POLVO LIOFILIZADO PARA SOLUCION INYECTABLEDronabinol
go.drugbank.com/drugs/DB00470ApprovedIllicitInvestigationalCB2 receptors are mainly located in the peripheral nervous system and can be found on lymphoid tissue where they are involved in regulation of immune function [A32676]. … Due to its evidence as an appetite stimulant and an anti-nauseant, Dronabinol is approved for use in anorexia associated with weight loss in patients with AIDS and for the treatment of nausea and vomiting
Categories: Analgesics, Non-Narcotic, P-glycoprotein inhibitorsSynonyms: 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol, 1-trans-delta-9-Tetrahydrocannabinol