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Imipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalTertiary amine TCAs, such as imipramine and amitriptyline, are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline and desipramine. … Imipramine has less sedative and anticholinergic effects than the tertiary amine TCAs, amitriptyline and clomipramine.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepineTinidazole
go.drugbank.com/drugs/DB00911ApprovedInvestigationalA nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Synonyms: 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazoleMixtures: GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADET, TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADETNateglinide
go.drugbank.com/drugs/DB00731ApprovedNateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). The major metabolites possess less activity than the parent compound. … In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control
Mixtures: NATMET 120/1000 MG TEDAVI PAKETI, 90+90 ADET, NATPLUS 180/1000 MG TEDAVI PAKETI, 90+90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalIt was first approved by the FDA in 2015. … [L40049] As vWF is normally present in the blood as a stable complex with coagulation factor III, therapeutic vWF products are also available as a combination product with [antihemophilic factor human]
Mixtures: BIOSTATE FOR INJECTION 50 iu/ml, Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for InjectionProducts: IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalOpiates such as codeine are derived from the poppy plant, _Papaver somniferum_ (Papaveraceae). … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.
Mixtures: A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADET, GERALGINE-K 500 MG/30 MG/10 MG TABLET, 20 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesRitonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalAlthough it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors … It is now more commonly used as a booster of other protease inhibitors and is available in both liquid formulations and as capsules.
Mixtures: KALETRA 200 MG/50 MG FILM TABLET, 120 ADET, Lopimune Tablets 200/50 mg (Lopinavir and Ritonavir Tablets 200/50 mg)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersDacarbazine
go.drugbank.com/drugs/DB00851ApprovedInvestigationalIt has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Synonyms: 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 4-(dimethyltriazeno)imidazole-5-carboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesEnoxaparin
go.drugbank.com/drugs/DB01225ApprovedInvestigationalEnoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection an...
Mixtures: ENOXAPARINA SODICA 40 MG JERINGAS PRELLENADASProducts: LOVENOX 10 x 4.000 IE (10 x 40 mg) Injektionslösung im Fertigpen, LOVENOX 10.000 IE (100 mg)/10 ml Injektionslösung in einer DurchstichflascheSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242412] It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor and immunosuppressive activities were later discovered, it was … [L39267] Sirolimus was also investigated in other cancers such as skin cancer, Kaposi’s Sarcoma, cutaneous T-cell lymphomas, and tuberous sclerosis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: RAPAMUNE 1 MG 100 FILM DRAJE, RAPAMUNE 0.5 MG TABLET ,100 ADETSucralfate
go.drugbank.com/drugs/DB00364ApprovedInvestigationalIt was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076]. … Sucralfate has been shown to be a well-tolerated and safe drug. It is sold under many brands and is available in both tablet and suspension forms.
Mixtures: CARDIBID®100/200 MG TABLETA RECUBIERTAProducts: ANTEPSİN 1 G/5 ML SÜSPANSİYON (100 ML), ALSUCRAL TABLETAS 500 MG