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Delandistrogene moxeparvovec
go.drugbank.com/drugs/DB16802ApprovedInvestigationalIt was granted accelerated approval by the FDA on June 22, 2023, as the first gene therapy to treat Duchenne Muscular Dystrophy (DMD).
Tabelecleucel
go.drugbank.com/drugs/DB17072ApprovedInvestigationalIt is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV).
Oveporexton
go.drugbank.com/drugs/DB21680Approved[L64068,L64069] It is the first orexin receptor agonist approved by the FDA and the first medicine to treat NT1 by targeting its underlying cause rather than individual symptoms.
CGC-11047
go.drugbank.com/drugs/DB05722InvestigationalCGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.
Dacetuzumab
go.drugbank.com/drugs/DB12589InvestigationalIt is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells.
Magnesium aspartate
go.drugbank.com/drugs/DB13359InvestigationalIt displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as magnesium citrate, magnesium carbonate and magnesium oxide.
Apramycin
go.drugbank.com/drugs/DB04626InvestigationalVet approvedIt is not approved for use in humans.
Tylosin
go.drugbank.com/drugs/DB11475ExperimentalVet approvedIt has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.
Ranirestat
go.drugbank.com/drugs/DB05327InvestigationalIt has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.
CCR5 mAb
go.drugbank.com/drugs/DB05906ExperimentalIt was generated by HGS using the Abgenix XenoMouse technology.