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Displaying results 4111 - 4120 of 8575 in total
  1. Drug

    TAS-108

    go.drugbank.com/drugs/DB05966
    Investigational

  2. Drug

    NOX-100

    go.drugbank.com/drugs/DB05799
    Investigational

    NOX-100 is the new nitric oxide (NO) neutralizing agent being developed by San Diego-based Medinox -- demonstrated its effectiveness and potential as a therapeutic to treat hemorrhagic shock. … NOX-100 is the first in a series of proprietary NO neutralizing compounds Medinox is developing to bind and inactivate NO, a simple gas molecule that is a key biological messenger in the body.

  3. Drug

    Evofosfamide

    go.drugbank.com/drugs/DB06091
    Investigational

    TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. … TH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide.

    Synonyms: (1-methyl-2-nitro-1H-imidazol-5-YL)methyl N,N'-bis(2-bromoethyl)diamidophosphate, (1-methyl-2-nitro-1H-imidazole-5-yl)methyl N,N'-bis(2-bromoethyl) diamidophosphate
  4. Drug

    Zenarestat

    go.drugbank.com/drugs/DB02132
    Experimental

  5. Drug

    Primaquine

    go.drugbank.com/drugs/DB01087
    ApprovedInvestigational

    It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria.

  6. Drug

    Olomorasib

    go.drugbank.com/drugs/DB21697
    Investigational

    Olomorasib has a monoisotopic molecular weight of 528.08 Da. … The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.

  7. Drug

    Frovatriptan

    go.drugbank.com/drugs/DB00998
    Approved

    Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.

  8. Drug

    Balsalazide

    go.drugbank.com/drugs/DB01014
    Approved

    Mesalazine is also known as 5-aminosalicylic acid, or 5-ASA. … It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine to the large intestine to act directly on ulcerative colitis.

  9. Drug

    FT516

    go.drugbank.com/drugs/DB15732
    Investigational

    This compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation.

  10. Drug

    BMS-754807

    go.drugbank.com/drugs/DB15399
    Investigational

    BMS-754807 is under investigation in clinical trial NCT00908024 (Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors).