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Dimethyltryptamine
go.drugbank.com/drugs/DB01488IllicitInvestigationalIt apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
BHV-1310
go.drugbank.com/drugs/DB22674ExperimentalBHV-1310 is a IgG1,2,4 selective degrader being investigated for the treatment of Grave's disease.
Elasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalThe Moderna COVID-19 Vaccine (mRNA-1273; Elasomeran) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavir...
Talizumab
go.drugbank.com/drugs/DB05797ExperimentalTNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.
SAR443122
go.drugbank.com/drugs/DB16492InvestigationalSAR443122, was investigated in several clinical trials to evaluate its safety and efficacy. NCT04469621 was studied in severe COVID-19 patients, while NCT05588843 is currently recruiting participants with ulcerative colitis. Additionally...
Placental Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15730InvestigationalIt was also found that fetal-side pMSCs express different surface markers. … It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells.
NasoVAX
go.drugbank.com/drugs/DB15859InvestigationalIt is a vaccine administered through a nasal spray that expresses influenza hemagglutinin in nasal epithelial cells[L16313]. … Created by Altimmune, Inc., NasoVAX is currently being developed for seasonal and pandemic use as it can activate humoral and cellular immune responses.
Cefovecin
go.drugbank.com/drugs/DB11505ExperimentalVet approvedIt is the first single-dose injectable antibiotic for dogs and cats that assures owner compliance with dosing for the animal. … It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs.
Matrix-M
go.drugbank.com/drugs/DB16369InvestigationalMatrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax. This compound is administered alongside vaccines to enhance biological functions: creating robust and long-last...
INCB13739
go.drugbank.com/drugs/DB05064InvestigationalIt is an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be critical to the development of type 2 diabetes