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Displaying results 4161 - 4170 of 10000 in total
  1. Drug

    Neostigmine

    go.drugbank.com/drugs/DB01400
    ApprovedInvestigationalVet approved

    A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.

    Synonyms: 3-Trimethylammoniumphenyl N,N-dimethylcarbamate, m-TrimethylammoniumphenyldimethylcarbamateProducts: NEOSTIGMINA METILSULFATO SOLUCION INYECTABLE DE 0.5 MG / 1 ML., NEOSTIGMINA 0. 5 MG / MLSOLUCION INYECTABLE
  2. Drug

    Cantuzumab mertansine

    go.drugbank.com/drugs/DB17239
    Experimental

    Synonyms: Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse monoclonal c242 light chain, dimer, compound with n(sup 2')-deacetyl-n(sup 2')-(3-mercapto-1-, Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulphide with human-mouse monoclonal c242 light chain, dimer, compound with n(sup 2')-deacetyl-n(sup 2')-(3-mercapto-1
  3. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19. … [A265040,A265045] It works by targeting B-cell-specific CD19 surface markers present on malignant B cells.

    Categories: Genetically-modified Autologous T Cells, CD19-Directed Genetically Modified Autologous T-cell ImmunotherapiesSynonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OBTAINED BY APHERESIS TRANSDUCED EX VIVO WITH A NON-REPLICATING, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING, A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING O
  4. Drug

    ONO-5334

    go.drugbank.com/drugs/DB19206
    Investigational

    ONO-5334 is under investigation in clinical trial NCT00532337 (Controlled Study of ONO-5334 in Postmenopausal Women With Osteopenia or Osteoporosis).

    Synonyms: N-((1S)-3-((2Z)-2-((4R)-3,4-DIMETHYL-1,3-THIAZOLIDIN-2-YLIDENE)HYDRAZINO)-2,3-DIOXO-1-(TETRAHYDRO-2H-PYRAN-4YL)PROPYL)CYCLOHEPTANECARBOXAMIDE
  5. Drug

    Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

    go.drugbank.com/drugs/DB14106
    ApprovedInvestigational

    Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]

    Synonyms: Tetrakis (2-methoxyisobutyl isonitrile) copper (I) tetrafluoroborate, Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborateProducts: MIBITEC 1 mg Kit für ein radioaktives Arzneimittel, CardioTOP 1 mg Kit für ein radioaktives Arzneimittel
  6. Drug

    Vinblastine

    go.drugbank.com/drugs/DB00570
    ApprovedInvestigational

    (Merck, 11th ed.)

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: VINBLASTINE RICHTER 5 MG FLAKON, VINBLASTINA10 MG X 1 FCO.
  7. Drug

    AZD-5153

    go.drugbank.com/drugs/DB17018
    Investigational

    Synonyms: 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl)-1,3-dimethyl-, (3r)-Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Dazucorilant

    go.drugbank.com/drugs/DB18025
    Investigational

    Synonyms: Methanone, ((4ar)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4ah-pyrazolo(3,4-g)isoquinolin-4a-yl)-2-pyridinyl-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    AC-003

    go.drugbank.com/drugs/DB22691
    Investigational

    AC-003 is a selective, oral small-molecule inhibitor of receptor-interacting protein kinase 1 (RIPK1). … [L53458] It is being investigated for the treatment of acute graft-versus-host disease (GVHD) and idiopathic pulmonary fibrosis (IPF).[L53458]

    Salts: Tetrahydro-2H-pyran-4-yl 7-(2-(cyclopropanecarboxamido)-imidazo[1,2-a]pyridin-6-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate hydrochlorideSynonyms: Tetrahydro-2H-pyran-4-yl 7-(2-(cyclopropanecarboxamido)- imidazo[1,2-a]pyridin-6-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate, Tetrahydro-2H-pyran-4-yl 7-(2-(cyclopropanecarboxamido)-imidazo[1,2-a]pyridin-6-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate
  10. Drug

    Narazaciclib

    go.drugbank.com/drugs/DB19038
    Investigational

    Narazaciclib is under investigation in clinical trial NCT06351644 (On 123300 (Narazaciclib) and Dexamethasone in Patients With Relapsed And/or Refractory Multiple Myeloma).

    Synonyms: Pyrido(2,3-d)pyrimidine-6-carbonitrile, 8-cyclopentyl-7,8-dihydro-2-((4-(4-methyl-1-piperazinyl)phenyl)amino)-7-oxo-