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Rotenone

Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.

Giredestrant

Giredestrant is under investigation in clinical trial NCT06065748 (A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With Er-positive

BOS172722

The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. … [A187120] An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.[A187123]

Piclidenoson

It is also being considered for the treatment of other autoimmune-inflammatory disorders, such as Crohn's disease, psorasis and dry eye syndrome. … CF101 is supplied as an oral drug and has an excellent safety profile.

Talmapimod

It has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.

TTP889

TTP889, an orally bioavailable selective inhibitor of the intrinsic coagulation pathway, is being developed as an anticoagulant for the treatment of thromboembolic disorders. … TTP889 has proven to be effective in preventing clot formation in several animal models of human disease, without any signs of the bleeding associated with traditional anticoagulants.

Calcium phosphate dihydrate

Trodusquemine

It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models [A176600].

PA-1050040

It inhibits virus replication by the same mechanism of action as BVM.

Tragacanth

Tragacanth allergenic extract is used in allergenic testing.