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Displaying results 4181 - 4190 of 10000 in total
  1. Drug

    Enmetazobactam

    go.drugbank.com/drugs/DB18716
    ApprovedInvestigational

    [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA on February 23, 2024, for the treatment of complicated urinary tract infections. … [A263266] Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious

  2. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. … [L43917] Famtozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineages BA.4 and BA.5.

    Categories: Complex Mixtures
  3. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    Andexanet alfa is currently under regulatory review by the European Union and is undergoing clinical development in Japan [A35518]. … It also prevents andexanet alfa from taking up space on phospholipid surface membranes, so that native FXa may bind and assemble the prothrominase complex [A35558].

  4. Drug

    Etretinate

    go.drugbank.com/drugs/DB00926
    ApprovedWithdrawn

    Etretinate was taken off the market in Canada in 1996 and America in 1998 due to the risk of birth defects. Etretinate is now used to treat T-cell lymphomas.

  5. Drug

    Moschus berezovskii musk sac resin

    go.drugbank.com/drugs/DB14247
    Investigational

    Moschus berezovskii musk sac resin is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Ma Ying Long Hemorrhoidal
  6. Drug

    (S)-camphor

    go.drugbank.com/drugs/DB11345
    Approved

    Camphor is a major active ingredient in over-the-counter balms and liniments supplied as topical analgesics by causing sensitization to heat and coolness to relieve minor muscle and joint pain [A33086]

  7. Drug

    Isocarboxazid

    go.drugbank.com/drugs/DB01247
    Approved

    [A31930] It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. … [T115] It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.

  8. Target

    Protein S100-A9

    go.drugbank.com/bio_entities/BE0008993
    TargetHumans

    Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme … The iNOS-S100A8/A9 transnitrosylase complex is proposed to also direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL

    Synonyms: Leukocyte L1 complex heavy chain
  9. Drug

    Vitis vinifera seed

    go.drugbank.com/drugs/DB16606
    Investigational

    Mixtures: Protect Plus SO 60Categories: Compounds used in a research, industrial, or household setting, Complex Mixtures
  10. Drug

    N,N'-diphenyl-1,4-phenylenediamine

    go.drugbank.com/drugs/DB14192
    Approved

    Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-diphenyl-1,4-phenylenediamine