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Displaying results 411 - 420 of 8170 in total
  1. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    [L6748] Opioid overdoses kill an average of 11 Canadians daily.[L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613]

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DUROGESIC D-TRANS, CITRATO DE FENTANILO 0.05MG/ML
  2. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. Since 2012, the extended-release ...

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2,3:4,5-di-O-isopropylidene-β-D-fructopyranose sulfamate, 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate
  3. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. … Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ESTRADERM TTS DE 100 MCG
  4. Drug

    Technetium Tc-99m etifenin

    go.drugbank.com/drugs/DB13183
    Investigational

    Products: EHIDA KIT PARA LA PREPARACIÓN DE RADIOFÁRMACOS.
  5. Drug

    Piroxicam

    go.drugbank.com/drugs/DB00554
    ApprovedInvestigational

    A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its lon...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: VERAN-D, PIROXICAM DR. REDDY'S
  6. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    Pyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s mechanism of action which competitively inhibits … Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods.

    Mixtures: Vitamine Du Groupe B Plus Fer - Liq, Se-Tan DHA
  7. Drug

    Meglumine antimoniate

    go.drugbank.com/drugs/DB13732
    Investigational

    Synonyms: Antimoniato de megluminaProducts: ANTIMONIATO DE MEGLUMINE1.5 G/ 5ML
  8. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one, (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
  9. Drug

    Fulvestrant

    go.drugbank.com/drugs/DB00947
    ApprovedInvestigational

    It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: FULVESTRANT DR. REDDY'S
  10. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.

    Mixtures: Allegra D-12 Hour, Allegra-DCategories: P-glycoprotein substrates