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Etavopivat
go.drugbank.com/drugs/DB18176InvestigationalEtavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Modipafant
go.drugbank.com/drugs/DB16237InvestigationalModipafant is under investigation in clinical trial NCT02569827 (Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore).
Mavelertinib
go.drugbank.com/drugs/DB16228InvestigationalMavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)).
Petrelintide
go.drugbank.com/drugs/DB19442InvestigationalPetrelintide is under investigation in clinical trial NCT06662539 (Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities).
Synonyms: 3,8-anhydro[N-(19-carboxynonadecanoyl)- L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L -lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-(2S)-α-2-aminoadipyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-arginyl, L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-5-carboxy-L-norvalyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-argi1,2-icosapentoyl-sn-glycero-3-phosphoserine
go.drugbank.com/drugs/DB14096ApprovedSalts: 1,2-icosapentoyl-sn-glycero-3-phosphoserine calciumMixtures: EnlLevorphanol
go.drugbank.com/drugs/DB00854ApprovedA narcotic analgesic that may be habit-forming. It is nearly as effective orally as by injection.
Categories: Heterocyclic Compounds with 4 or More Rings105AD7
go.drugbank.com/drugs/DB05113Investigationalmetastatic colorectal cancer patients. 105AD7 may be a suitable vaccine for treatment of this disease. … 105AD7 is a human monoclonal antibody that mimics the complement regulatory protein, CD55, overexpressed by many solid tumours including osteosarcoma. 105AD7 induced antitumour inflammatory responses in
CXD101
go.drugbank.com/drugs/DB16182InvestigationalCXD101 is under investigation in clinical trial NCT03873025 (A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-cell Lymphoma).
Synonyms: Hdac-in-4Cephaloglycin
go.drugbank.com/drugs/DB00689ApprovedA cephalorsporin antibiotic that is no longer commonly used.