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Displaying results 4201 - 4210 of 8469 in total
  1. Drug

    Vusolimogene oderparepvec

    go.drugbank.com/drugs/DB23008
    ApprovedInvestigational

    [L64061] The virus is engineered to express a fusogenic glycoprotein derived from gibbon ape leukemia virus (GALV-GP-R–) and human granulocyte-macrophage colony-stimulating factor (GM-CSF), and has its … [L64061,L64062] It is the second oncolytic viral therapy approved in the United States, following talimogene laherparepvec (T-VEC, Imlygic) in 2015, and the first approved for melanoma that has progressed

  2. Drug

    Ciltacabtagene autoleucel

    go.drugbank.com/drugs/DB16738
    ApprovedInvestigational

    [A245854] Carvykti was first approved by the FDA in February 2022 for the treatment of relapsed or refractory multiple myeloma in treatment-experienced patients.[L40744] … [A245854] B-cell maturation antigen (BCMA) is a transmembrane glycoprotein member of the tumor necrosis factor receptor superfamily 17 (TNFRSF17) which is used as a biomarker for multiple myeloma.

  3. Drug

    BacTRL-spike

    go.drugbank.com/drugs/DB15811
    Investigational

    The vaccine was developed by Symvivo Corporation. … As of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to test the safety and immunogenicity of the vaccine.

  4. Drug

    Cintredekin besudotox

    go.drugbank.com/drugs/DB05305
    Investigational

    Cintredekin besudotox has been developed as a specific tumor-targeting agent, which is administered by positive-pressure convection-enhanced delivery (CED) directly to brain tissue at risk for residual

  5. Drug

    Casdatifan

    go.drugbank.com/drugs/DB21701
    Investigational

    Casdatifan has a monoisotopic molecular weight of 439.09 Da. … Casdatifan is under investigation in clinical trial NCT07000149 (A Study to Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC)

  6. Drug

    Iferanserin

    go.drugbank.com/drugs/DB11686
    Investigational

    Iferanserin has been investigated for the treatment of Hemorrhoids.

  7. Drug

    Artefenomel

    go.drugbank.com/drugs/DB11809
    Investigational

    Artefenomel has been investigated for the treatment of Malaria.

  8. Drug

    RO-5028442

    go.drugbank.com/drugs/DB12721
    Investigational

    RO5028442 has been used in trials studying Autistic Disorder.

  9. Drug

    ACT-451840

    go.drugbank.com/drugs/DB13054
    Investigational

    ACT-451840 has been used in trials studying Malaria.

  10. Drug

    Lupeol

    go.drugbank.com/drugs/DB12622
    Investigational

    Lupeol has been investigated for the treatment of Acne.