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Bamocaftor
go.drugbank.com/drugs/DB15177InvestigationalBamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).
Synonyms: N-(benzenesulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide, 3-Pyridinecarboxamide, N-(phenylsulfonyl)-6-(3-(2-(1-(trifluoromethyl)cyclopropyl)ethoxy)-1H-pyrazol-1-yl)-2-((4S)-2,2,4-trimethyl-1-pyrrolidinyl)-Categories: Heterocyclic Compounds, 1-RingCalcitonin gene-related peptide
go.drugbank.com/drugs/DB06379InvestigationalA 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. … In particular, it is a potent endogenous vasodilator.
Dasiglucagon
go.drugbank.com/drugs/DB15226ApprovedAlthough it tends to be more common in type 1 diabetes mellitus, occurring in about 22% to 46% of patients annually, about 7% to 25% of patients with type 2 diabetes mellitus treated with insulin experience … severe hypoglycemia a year.
Categories: Sex Hormones and InsulinsDeferitrin
go.drugbank.com/drugs/DB16132InvestigationalDeferitrin is under investigation in clinical trial NCT00069862 (Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-thalassemia).
Categories: Heterocyclic Compounds, 1-RingNaporafenib
go.drugbank.com/drugs/DB18865InvestigationalNaporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).
Synonyms: N-(3-(2-(hydroxyethoxy)-6-(morpholin-4-yl) pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)pyridine-4-carboxamide, 4-pyridinecarboxamide, n-(3-(2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl)-4-methylphenyl)-2-(trifluoromethyl)-)-Categories: Heterocyclic Compounds, 1-RingNoscapine
go.drugbank.com/drugs/DB06174ApprovedSynonyms: (−)-α-narcotineMixtures: COLDEKS KAPSUL, 20 ADET, NEUMOLEX® NFPX-102
go.drugbank.com/drugs/DB15416InvestigationalPX-102 is under investigation in clinical trial NCT01998672 (Multiple Ascending Oral Dose Phase I Study With Px-102).
Categories: Heterocyclic Compounds, 1-RingHX-1171
go.drugbank.com/drugs/DB12162InvestigationalHx 1171 is under investigation in clinical trial NCT01548391 (A Phase I Clinical Study Study of the Safety, Tolerability, and Pharmacokinetics of HX-1171 in Healthy Male Subjects).
Benzophenone
go.drugbank.com/drugs/DB01878ApprovedBenzophenone is the organic compound. Substituted benzophenones such as oxybenzone and dioxybenzone are used in sunscreen.
Synonyms: α-oxoditane, α-oxodiphenylmethaneMixtures: nanocare Moisturizing Sunscreen SPF 50, nanocare Moisturizing Sunscreen SPF 50Gefapixant
go.drugbank.com/drugs/DB15097Approved[L48596,L48591] It is the first therapy to be approved for the treatment of RCC or UCC in the EU.[L48601] … It has been estimated that 5-10% of adults globally suffer from chronic cough, which is defined as a cough lasting longer than eight weeks.
Categories: MATE 1 Substrates, MATE 2 Substrates