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Displaying results 4211 - 4220 of 10000 in total
  1. Target

    Capsid protein

    go.drugbank.com/bio_entities/BE0010951
    TargetHepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979)

    Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin

    Synonyms: Core antigen, Core protein
  2. Drug

    Sodium lauryl sulfoacetate

    go.drugbank.com/drugs/DB13157
    ApprovedWithdrawn

    Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.

  3. Drug

    Cloridarol

    go.drugbank.com/drugs/DB13291
    Experimental

    Cloridarol is an experimental medication in the treatment of heart disease, which acts through vasodilation. It was studied for the treatment of coronary insufficiency in Italy in the 1970s [A176222].

    Categories: Vasodilators Used in Cardiac Diseases
  4. Drug

    Ammonium molybdate

    go.drugbank.com/drugs/DB11128
    Investigational

    Molybdenum is an essential element that is present in enzymes including xanthine oxidase, sulfite oxidase, and aldehyde oxidase. … Ammonium molybdate is a source of molybdenum that exists in several hydrate forms. It is intravenously administered as an additive to solutions for Total Parenteral Nutrition (TPN).

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Cosibelimab

    go.drugbank.com/drugs/DB15770
    ApprovedInvestigational

    On December 13, 2024, cosibelimab was approved by the FDA for the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma [L52690] as the first approved anti-PD-L1 therapy in the

  6. Drug

    Batroxobin

    go.drugbank.com/drugs/DB09005
    Investigational

    In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. … Recombinant Batroxobin in relatively affordable and could be accessed by mass production.

    Categories: Complex Mixtures
  7. Drug

    Safflower oil

    go.drugbank.com/drugs/DB09446
    ApprovedInvestigationalWithdrawn

    Safflower (_Carthamus tinctorius_ L) is a herbaceous plant in the Asteraceae family. … Safflower oil is approved for use as an indirect additive in food contact substances and is readily available as a food ingredient.

    Mixtures: Liposyn II 20%Categories: Complex Mixtures
  8. Drug

    Trapidil

    go.drugbank.com/drugs/DB09283
    Experimental

    Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.

    Categories: Vasodilators Used in Cardiac Diseases
  9. Drug

    Technetium Tc-99m mebrofenin

    go.drugbank.com/drugs/DB09137
    ApprovedWithdrawn

    Liver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic uptake and fast biliary excretion, resulting in improved hepatic imaging.

    Categories: Compounds used in a research, industrial, or household setting
  10. Target

    Hyaluronidase enzymes

    go.drugbank.com/bio_entities/BE0010043
    EnzymeTargetHumans

    Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 10-5 kDa fragments (PubMed:37527776). Very specific to hyaluronan; not abl...

    Polypeptides: Hyaluronidase PH-20Synonyms: Sperm surface protein PH-20, Hyaluronoglucosaminidase PH-20