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Displaying results 4211 - 4220 of 10000 in total
  1. Target

    DNA gyrase subunit A

    go.drugbank.com/bio_entities/BE0008387
    TargetBacillus subtilis (strain 168)

    A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.

    Polypeptides: DNA gyrase subunit A
  2. Target

    Inhibin beta A chain

    go.drugbank.com/bio_entities/BE0010139
    TargetHumans

    Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid

    Polypeptides: Inhibin beta A chainSynonyms: Activin beta-A chain
  3. Target

    Human Arylsulfatase A mRNA

    go.drugbank.com/bio_entities/BE0010214
    TargetHumans

  4. Target

    Interleukin-17 receptor A

    go.drugbank.com/bio_entities/BE0018249
    TargetHumans

    Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848) … Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (PubMed:16785495).

    Polypeptides: Interleukin-17 receptor ASynonyms: IL-17 receptor A
  5. Drug

    Fluorouracil

    go.drugbank.com/drugs/DB00544
    ApprovedInvestigational

    A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.

    Mixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, VERRUTOL %0,5 + %10 DERİ ÇÖZELTİSİ (15 G)Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index
  6. Drug

    Anbenitamab

    go.drugbank.com/drugs/DB18411
    Investigational

    Synonyms: FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific IgG1 antibody inhibiting PD-L1 and CTLA-4, IMMUNOGLOBULIN G1 (369-SERINE,371-ALANINE,408-LYSINE,410-VALINE), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR HER2 DOMAIN IV)(HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS
  7. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. … for an extended period.

    Mixtures: DEPALGOS® 5 MG /325 MG, Targin 10 mg/5 mg RetardtablettenCategories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 Substrates
  8. Drug

    Lorigerlimab

    go.drugbank.com/drugs/DB18942
    Investigational

    Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).

    Synonyms: MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC,, -CHAIN V-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GGGSGGGG) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEI
  9. Drug

    Flumazenil

    go.drugbank.com/drugs/DB01205
    ApprovedInvestigational

    Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine … receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET, ANEXATE 0,5 MG/5 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET
  10. Indication

    Molybdenum Cofactor Deficiency, Type A

    go.drugbank.com/conditions/DBCOND0067628
    Drugs: Fosdenopterin
    Synonyms: Molybdenum Cofactor Deficiency, Type A, Molybdenum Cofactor Deficiency Type A