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Norclozapine

It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition, thereby addressing one of the major challenges in treating schizophrenia today.

ZEN-012

It is developed for the treatment of solid tumors.

Eflepedocokin alfa

[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).[L27666]

OTL-201

It consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.[L45973]

KOS-2187

KOS-2187, a novel erythromycin-based motilin agonist, or motilide, as a clinical candidate for the treatment of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease (GERD).

Trestolone

Trestolone (7α-methyl-19-nortestosterone) is a synthetic androgen developed by the Population Council as a potential candidate drug for use in hormonal male contraceptive methods. In males, regular administration of sufficient quantities...

Trafermin

Amfecloral

For a short period of time, it was available under the brand Acutran and indicated as an appetite suppressant, but this product no longer exists. … It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the N-substituent, in this case, yields a compound that is active

Spermine

Found in various tissues and organisms, it often acts as an essential growth factor in some bacterial species.

4'-Methylene-5,8,10-trideazaaminopterin

It has been investigated for the treatment of Rheumatoid Arthritis (phase II).