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Amedalin
go.drugbank.com/drugs/DB09188ExperimentalIt has no significant effect on reuptake of serotonin and dopamine and no antihistamine or anticholinergic properties. This drug was never marketed. … Amedalin is a selective norepinephrine reuptake inhibitor developed in the 1970s.
Paricalcitol
go.drugbank.com/drugs/DB00910ApprovedInvestigationalParicalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Edetate disodium anhydrous
go.drugbank.com/drugs/DB14600ApprovedInvestigationalVet approvedEdetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Boron
go.drugbank.com/drugs/DB11203ApprovedInvestigationalThere are few pharmaceutical agents that contain a boron molecule in their structures, such as [DB09041] and [DB00188]. … Boric acid contains antiseptic, antifungal, and antiviral properties thus it is used as a water clarifier in swimming pool water treatment.
Mixtures: Ribotin-EButylphthalide
go.drugbank.com/drugs/DB12749InvestigationalButylphthalide has been used in trials studying the prevention of Restenosis.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 3-n-butylphthalide, DL-3-n-butylphthalideEliprodil
go.drugbank.com/drugs/DB12869InvestigationalEliprodil has been used in trials studying the treatment of Parkinson Disease and Movement Disorders.
Categories: Compounds used in a research, industrial, or household settingLX1031
go.drugbank.com/drugs/DB05199InvestigationalLX1031 was generated by Lexicon medicinal chemists, and its target was internally identified as a key control point for the regulation of peripheral serotonin levels. … LX1031 is designed to act locally in the gastrointestinal tract by reducing the serotonin available for receptor activation, without affecting serotonin levels in the brain or its central nervous system
FRAX716
go.drugbank.com/drugs/DB31795ExperimentalFRAX716 is a group I-specific p21-activated kinase (PAK) inhibitor which dramatically inhibits the phosphorylation of PAK and Mek1.[A274678]
R450
go.drugbank.com/drugs/DB05469ExperimentalR450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence.
ASI402
go.drugbank.com/drugs/DB06373InvestigationalASI402 is a monoclonal antibody that targets an aberrantly glycosylated antigen Mucin 1. It is being investigated in cancers.