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Nabilone
go.drugbank.com/drugs/DB00486ApprovedInvestigationalNabilone is a racemate consisting of the (S,S) and the (R,R) isomers. … Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: Canemes 1 mg KapselnPefloxacin
go.drugbank.com/drugs/DB00487ApprovedA synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: N/A, LAVUZID® NCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions.
Synonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.
Synonyms: 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-oneMixtures: DEPALGOS® 5 MG /325 MG, SENIDOL ®Ritonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalAny HCV/HIV-1 co-infected patients treated with ritonavir-containing combination therapies should also be on a suppressive antiretroviral drug regimen to reduce the risk of HIV-1 protease inhibitor drug … and 4 treatment-naïve patients with or without cirrhosis.
Mixtures: ANCEF ® R, ANCEF ® RCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment … Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and
Categories: Heterocyclic Compounds, 1-RingProducts: N/a, VIBATRIN® 100 MG / 5 MLTriflupromazine
go.drugbank.com/drugs/DB00508ApprovedVet approvedA phenothiazine used as an antipsychotic agent and as an antiemetic.
Synonyms: 10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine, 2-(Trifluoromethyl)promazineCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approvedA benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Synonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate, 5-(propylthio)-2-carbomethoxyaminobenzimidazoleInternational brands: Ben-AAlitretinoin
go.drugbank.com/drugs/DB00523ApprovedTretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic.
Synonyms: 9(Z)-Retinoic acid, (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acidMixtures: Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05%