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Displaying results 4261 - 4270 of 10000 in total
  1. Drug

    EGT-201

    go.drugbank.com/drugs/DB17648
    Experimental

    EGT-201 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the alpha-N-acetyglucosaminidase (NAGLU) transgene. … Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type B.[L45939]

    Synonyms: EGT 201
  2. Drug

    NOV-002

    go.drugbank.com/drugs/DB05393
    Investigational

    It has been administered to over 10,000 patients, demonstrating clinical efficacy and excellent safety data. … NOV-002, the lead compound acts as a chemoprotectant and an immunomodulator, in combination with chemotherapy.

  3. Drug

    Tolperisone

    go.drugbank.com/drugs/DB06264
    Investigational

    It possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves. … Tolperisone is an oral, centrally acting muscle relaxant. Its precise mechanism is not completely understood, though it blocks sodium and calcium channels.

    Products: TOLPERISON-NEURAX 50 MG, TOLPERISON-NEURAX 150 MG
  4. Drug

    PSN9301

    go.drugbank.com/drugs/DB05001
    Experimental

    PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for meal-related dosing. … PSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes.

  5. Drug

    Calcimycin

    go.drugbank.com/drugs/DB19408
    Investigational

    It binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in rat liver mitochondria. … Calcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Sage oil

    go.drugbank.com/drugs/DB11199
    ApprovedNutraceutical

    It is found in cosmetics, personal care products and dietary supplements. … Essential oil has been traditionally used in medicine for the relief of pain and the treatment of inflammation and infections, as it is reported to exhibit carminative, antispasmodic, antiseptic, and astringent

  7. Drug

    Fosinoprilat

    go.drugbank.com/drugs/DB14207
    Experimental

    Fosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.

    Categories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Rice bran oil

    go.drugbank.com/drugs/DB11293
    ApprovedInvestigational

    Rice bran oil is classified as an indirect additive used in food contact substances by the FDA. … It contains monosaturated fatty acids, polyunsaturated fatty acids, and saturated fatty acids.

  9. Drug

    Sinapic acid

    go.drugbank.com/drugs/DB08587
    Experimental

    It is also a constituent of propolis.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid
  10. Drug

    PG-530742

    go.drugbank.com/drugs/DB05495
    Investigational

    By inhibiting these MMPs, it potentially limits cartilage degradation and disease progression. … PG-530742 selectively inhibits certain matrix metalloproteinases that have been implicated in the cartilage degradation that occurs in osteoarthritis.