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Mipomersen
go.drugbank.com/drugs/DB05528ApprovedIt is marketed under the brand name Kynamro in the United States, and the FDA label includes a black box warning of hepatoxicity.
Desmoteplase
go.drugbank.com/drugs/DB04925InvestigationalWhen a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. … It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots.
AZD 3355
go.drugbank.com/drugs/DB05404InvestigationalIt is developed by AstraZeneca and is currently in phase I/II trials.
Asvasiran
go.drugbank.com/drugs/DB05638InvestigationalIt has the potential to treat or prevent RSV infection.
Dimethylcurcumin
go.drugbank.com/drugs/DB06133InvestigationalIt is a novel anti-androgen that enhances androgen receptor degradation.
Cythioate
go.drugbank.com/drugs/DB11392ExperimentalVet approvedIt is mainly used in veterinary as a treatment for fleas.
AEM-28
go.drugbank.com/drugs/DB17642InvestigationalAEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.[A258764]
Reloxiliase
go.drugbank.com/drugs/DB17653ExperimentalIt is being investigated for the treatment of hyperoxaluria.[A258823]
WP-1301
go.drugbank.com/drugs/DB17702ExperimentalIt binds to an MHC class II molecule and is recognized by a Factor VIII-specific T cell.[L46138]
ALT-P1
go.drugbank.com/drugs/DB18485InvestigationalIt is under investigation for the treatment of growth hormone deficiency.