Dimethylcurcumin

DB06133InvestigationalSmall molecule

Dimethylcurcumin is a synthetic chemical compound that is loosely based on a compound found in curcumin. It is a novel anti-androgen that enhances androgen receptor degradation.

Mechanism: Pharmacologically active on Androgen receptor
Curator reviewed
Primary indication: Investigated for use/treatment in acne and alopecia.Curator reviewed
Formula / weight: C₂₃H₂₄O₆ · 396.439 g/mol (avg)
Code names: ASC-J9 · CHC-004 · GO-Y-025

Resolves to

Compound

UNIID60XLY608DCAS52328-98-0ChEMBLCHEMBL128748

Structure

InChIKeyZMGUKFHHNQMKJI-CIOHCNBKSA-NSMILESCOC1=CC=C(\C=C\C(\O)=C\C(=O)\C=C\C2=CC(OC)=C(OC)C=C2)C=C1OC

Targets

P10275AR

What you can answer from here — as of June 12, 2020

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Dimethylcurcumin, and which of those have an active Phase 3 trial?

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