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Lomedeucitinib
go.drugbank.com/drugs/DB21649InvestigationalLomedeucitinib is under investigation in clinical trial NCT05730725 (A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis).
Limaprost
go.drugbank.com/drugs/DB09211InvestigationalOno and DSP also discontinued the development of limaprost alfadex for the additional indication of cervical spondylosis in 2008 due to the failure to demonstrate the anticipated efficacy in a Phase II … In 2013, these trials were discontinued because the study failed to demonstrate efficacy.
Adecatumumab
go.drugbank.com/drugs/DB05006InvestigationalAdecatumumab is a recombinant human monoclonal antibody of the IgG1 subclass with a binding specificity to epithelial cell adhesion molecule (EpCAM).
Iomazenil
go.drugbank.com/drugs/DB14971InvestigationalIomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans).
AMZ002
go.drugbank.com/drugs/DB17017InvestigationalAMZ002 is a sterile injectable hormone developed as a purified synthetic polypeptide alternative to current FDA-approved epileptic seizure treatments.
Xaluritamig
go.drugbank.com/drugs/DB18137InvestigationalXaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
RC118
go.drugbank.com/drugs/DB18428InvestigationalRC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
GYM329
go.drugbank.com/drugs/DB18590InvestigationalGYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Synonyms: recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent mannerExicorilant
go.drugbank.com/drugs/DB16162InvestigationalExicorilant is under investigation in clinical trial NCT03437941 (Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With Mcrpc).
TNP-2092
go.drugbank.com/drugs/DB16312InvestigationalTNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).