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Displaying results 421 - 430 of 10000 in total
  1. Drug

    Pirtobrutinib

    go.drugbank.com/drugs/DB17472
    ApprovedInvestigational

    Pirtobrutinib is a small molecule and a highly selective non-covalent inhibitor of Bruton’s tyrosine kinase (BTK). … [A256758] Unlike BTK covalent inhibitors, such as [ibrutinib], that bind to the cysteine 481 (Cys481) amino acid within the active site of BTK, the inhibitory activity of pirtobrutinib is maintained even

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1h-pyrazole-4-carboxamide, 1h-pyrazole-4-carboxamide, 5-amino-3-(4-(((5-fluoro-2-methoxybenzoyl)amino)methyl)phenyl)-1-((1s)-2,2,2-trifluoro-1-methylethyl)-
  2. Drug

    Mimosine

    go.drugbank.com/drugs/DB01055
    Experimental

    Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (S)-2-amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate, (L)-Mimosine
  3. Drug

    L-2-aminopimelic acid

    go.drugbank.com/drugs/DB03134
    Experimental

    Synonyms: (S)-2-aminoheptanedioic acid, L-2-aminopimelic acid
  4. Drug

    AR-42

    go.drugbank.com/drugs/DB12707
    Investigational

    AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and Vestibular Schwannoma, among others.

    Synonyms: (S)-(+)-N-HYDROXY-4-(3-METHYL-2-PHENYL-BUTYRYLAMINO)-BENZAMIDE, N-Hydroxy-4-(3-methyl-2-(S)phenyl-butyrylamino)benzamide
  5. Drug

    (S)-2-CHLORO-N-(1-(2-(2-HYDROXYETHYLAMINO)-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE

    go.drugbank.com/drugs/DB07792
    Experimental

    Synonyms: (S)-2-CHLORO-N-(1-(2-(2-HYDROXYETHYLAMINO)-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE
  6. Drug

    1-Naphthyl-L-alanine

    go.drugbank.com/drugs/DB07365
    Experimental

    Synonyms: (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid, 1-Naphthyl-L-alanine
  7. Drug

    Romlusevimab

    go.drugbank.com/drugs/DB16494
    Investigational

    Romlusevimab (BRII-198) was under investigation in clinical trials (NCT04479644 and NCT04691180) to treat COVID-19, focusing on its safety, tolerability, and pharmacokinetics.

    Synonyms: IMMUNOGLOBULIN G1-LAMBDA2, ANTI-(SEVERE ACUTE RESPIRATORYSYNDROME CORONAVIRUS 2 (SARS-COV-2) SPIKE (S) GLYCOPROTEIN,RECEPTOR BINDING DOMAIN (RBD)), HOMO SAPIENS MONOCLONALANTIBODY
  8. Drug

    DPI-221

    go.drugbank.com/drugs/DB06121
    Experimental

    DPI-221 is an investigational drug and a selective agonist for the δ-opioid receptor.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: BENZAMIDE, N,N-DIETHYL-4-((S)-((2S,5R)-4-((3-FLUOROPHENYL)METHYL)-2,5-DIMETHYL-1-PIPERAZINYL)PHENYLMETHYL)-, N,N-DIETHYL-4-((S)-((2S,5R)-4-((3-FLUOROPHENYL)METHYL)-2,5-DIMETHYL-1-PIPERAZINYL)PHENYLMETHYL)BENZAMIDE
  9. Drug

    Ukrain cation

    go.drugbank.com/drugs/DB17150
    Experimental

    Synonyms: s,12bs,12'bs,12''bs)-, (1,3)benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13,13',13''-(phosphinothioylidynetris(imino-2,1-ethanediyl))tris(5b,6,7,12b,13,14-hexahydro-6-hydroxy-13-methyl-, (5br,5'br,5''br,6s,6's,6''Categories: Heterocyclic Compounds, 3-Ring, Heterocyclic Compounds with 4 or More Rings
  10. Drug

    Tocofersolan

    go.drugbank.com/drugs/DB11635
    Approved

    D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis [L2371]. … It was approved by the European Medicines Agency (EMA) in June 2009 under the market name Vedrop.

    Mixtures: Eye Health Areds 2 FormulaCategories: Vitamin E, Cytochrome P-450 Substrates