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Cycrimine
go.drugbank.com/drugs/DB00942ApprovedCycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.
Lexibulin
go.drugbank.com/drugs/DB05147InvestigationalCYT997 is an orally available vascular targeting and cytotoxic agent that has proven effective in animal models of a wide range of tumour types including breast, prostate and colon, as well as some leukemias
Tertomotide
go.drugbank.com/drugs/DB12747InvestigationalTertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma). … It is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells. It is being developed by Pharmexa A/S.
Rimiducid
go.drugbank.com/drugs/DB04974InvestigationalRimiducid is a lipid-permeable tacrolimus analogue and a protein dimerizer. … [A187496,L9521] The combination use of rimiducid with immunotherapies for enhanced therapeutic effectiveness is currently under investigation.
Dexpramipexole
go.drugbank.com/drugs/DB15130InvestigationalDexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured
Categories: Compounds used in a research, industrial, or household settingADH-1
go.drugbank.com/drugs/DB05485InvestigationalADH-1 may have utility in a wide variety of cancers as N-cadherin is overexpressed in a variety of tumors. … ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models.
Synonyms: l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfideCoumaphos
go.drugbank.com/drugs/DB11390ExperimentalVet approvedThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a _dip_ or _wash_. … Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas.
Categories: Compounds used in a research, industrial, or household settingPemivibart
go.drugbank.com/drugs/DB18720Investigational[L50326] It received emergency use authorization (EUA) from the FDA in March 2024 for pre-exposure prophylaxis (PrEP) of COVID-19 in certain high-risk patient populations. … [L51733] Due to the amino acid substitutions in the Fc region (M435L/N441A), pemivibart has an extended serum half-life.[L51728]