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CA-074 methyl ester
go.drugbank.com/drugs/DB07223ExperimentalIt is converted by cellular esterases to CA-074.[A258234,A258239]
Synonyms: Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate, L-Proline, N-[[(2S,3S)-3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl-, methyl esterFluorofuranylnorprogesterone F-18
go.drugbank.com/drugs/DB15282InvestigationalFluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).
Butyrylthiocholine
go.drugbank.com/drugs/DB04250ExperimentalA sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity.
Utidelone
go.drugbank.com/drugs/DB17575InvestigationalUtidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.
mRNA-3705
go.drugbank.com/drugs/DB17668InvestigationalDeveloped by Moderna TX Inc., it is being investigated for the treatment of methylmalonic academia.[A258843]
RLYB212
go.drugbank.com/drugs/DB17727InvestigationalIt is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
SAR-439459
go.drugbank.com/drugs/DB17864Investigational[A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.
Moricizine
go.drugbank.com/drugs/DB00680ApprovedWithdrawnAn antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Synonyms: ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamateDPDPE
go.drugbank.com/drugs/DB08861ExperimentalA heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
Foscarnet
go.drugbank.com/drugs/DB00529ApprovedInvestigationalAn antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.