DPDPE

DB08861ExperimentalSmall molecule

A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.

Chemical structure of DPDPE
Formula / weight
C30H39N5O7S2 · 645.79 g/mol (avg)
Also known as
2,5-Pen-enkephalin

Resolves to

Structure
InChIKeyMCMMCRYPQBNCPH-WMIMKTLMSA-NSMILESCC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)CC2=CC=C(O)C=C2)C(=O)NCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H]1C(O)=O
Transporters

What you can answer from here — as of April 02, 2025

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
920Drug interactionsStructured to mechanism, not free text
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14+ReferencesStructured and connected to the statements they support
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Which drugs share a target with DPDPE, and which of those have an active Phase 3 trial?

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