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Displaying results 4331 - 4340 of 8700 in total
  1. Drug

    Macelignan

    go.drugbank.com/drugs/DB14129
    Investigational

    Macelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.

    Mixtures: O HUI white-skin science white calming maskCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Estradiol benzoate

    go.drugbank.com/drugs/DB13953
    ApprovedVet approvedWithdrawn

    [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%). … As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located

    Categories: Hormonal Contraceptives for Systemic Use, P-glycoprotein substrates
  3. Drug

    Pleconaril

    go.drugbank.com/drugs/DB05105
    Investigational

    Pleconaril is an antiviral drug from _viral capsid inhibitor_ class, manufactured by _Schering-Plough_ and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic … Food and Drug Administration (FDA) due to the fact that it has been found to induce CYP3A enzyme activity, therefore increasing the risk for serious drug interactions.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  4. Drug

    Tenamfetamine

    go.drugbank.com/drugs/DB01509
    IllicitInvestigational

    It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem] … An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen.

  5. Drug

    Corticorelin

    go.drugbank.com/drugs/DB05394
    Investigational

    Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone, also called hCRF. … It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory.

    Categories: Tests for Pituitary FunctionProducts: CRH "Ferring" - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung
  6. Drug

    N-Acetylglucosamine

    go.drugbank.com/drugs/DB00141
    ApprovedInvestigationalNutraceutical

    The N-acetyl derivative of glucosamine.

  7. Drug

    FM-VP4

    go.drugbank.com/drugs/DB05449
    Investigational

    Additional experiments suggest that FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride levels, reduce weight gain and exert a anti-atherosclerosis effect.

  8. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymeras...

    Categories: Antiinfectives for Systemic Use, Drugs for Treatment of LepraProducts: Rifoldin 600 mg Trockensubstanz zur Infusionsbereitung mit Lösungsmittel
  9. Drug

    Chloroform

    go.drugbank.com/drugs/DB11387
    ApprovedVet approvedWithdrawn

    Chloroform is part of the FDA drug products withdrawn or removed from the market for reasons of safety or effectiveness.[L43942] … Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
  10. Drug

    Rapacuronium

    go.drugbank.com/drugs/DB04834
    ApprovedWithdrawn

    Rapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm.