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Displaying results 4341 - 4350 of 10000 in total
  1. Drug

    XL281

    go.drugbank.com/drugs/DB05190
    Investigational

    XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated in 60 percent of melanomas, 24-44 percent of thyroid cancers, and 9 percent of colon cancers. … XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway.

  2. Drug

    Sobuzoxane

    go.drugbank.com/drugs/DB21119
    Experimental

    Sobuzoxane is a small molecule drug. The usage of the INN stem '-oxan(e)' in the name indicates that Sobuzoxane is a benzodioxane derivative. … Sobuzoxane has a monoisotopic molecular weight of 514.23 Da.

    Categories: Topoisomerase II Inhibitors
  3. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedInvestigationalWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    International brands: Terfenadin ALProducts: Seldane 120mg Once-A-day Caplets, Allergy Relief Once A Day Allergy Caplet 120mg
  4. Drug

    Ferrous glycine sulfate

    go.drugbank.com/drugs/DB14501
    Approved

    Synonyms: Iron(II) glycine sulfate, Ferrous (II) Glycine Sulphate Complex
  5. Drug

    Peptide YY (3-36)

    go.drugbank.com/drugs/DB05004
    Investigational

    Peptide YY (3-36), a synthetic human PYY 3-36, is a compound being evaluated for the treatment of obesity. It reduces appetite and increases satiety in obese patients.

  6. Drug

    Phenobarbital

    go.drugbank.com/drugs/DB01174
    ApprovedInvestigational

    A barbituric acid derivative that acts as a nonselective central nervous system depressant. … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index
  7. Drug

    Potassium permanganate

    go.drugbank.com/drugs/DB13831
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Dipicolinic acid

    go.drugbank.com/drugs/DB04267
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    ETC-1001

    go.drugbank.com/drugs/DB05866
    Experimental

    ETC-1001 is Pfizer’s lead oral small molecule product candidate which is intended to be a chronic treatment for individuals with lipid disorders.

  10. Drug

    Proparacaine

    go.drugbank.com/drugs/DB00807
    ApprovedVet approved

    Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.