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Displaying results 4341 - 4350 of 10000 in total
  1. Drug

    Nitroprusside

    go.drugbank.com/drugs/DB00325
    ApprovedInvestigational

    Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.

    Categories: Compounds used in a research, industrial, or household setting, Arteriolar Smooth Muscle, Agents Acting OnProducts: NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE, NITROPRUSIATO DE SODIO INYECTABLE 25 MG/ML
  2. Drug

    Divozilimab

    go.drugbank.com/drugs/DB18878
    Investigational

    Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)).

    Synonyms: Immunoglobulin g1, anti-(human cd20 antigen) (human-mus musculus monoclonal bcd-132 .gamma.1-chain), disulfide with human-mus musculus monoclonal bcd-132 .kappa.-chain, dimer
  3. Drug

    Galegenimab

    go.drugbank.com/drugs/DB18860
    Investigational

    Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to

    Synonyms: Immunoglobulin igg1 fab fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal fhtr2163 .gamma.1-chain), disulfide with human-mus musculus monoclonal fhtr2163 .kappa.-chain
  4. Drug

    Phenolphthalein

    go.drugbank.com/drugs/DB04824
    ApprovedWithdrawn

    Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.

    Synonyms: 3,3-Bis(4-hydroxyphenyl)phthalideInternational brands: Feen-a-mint gum, Feen-a-mint laxative mints
  5. Drug

    Paricalcitol

    go.drugbank.com/drugs/DB00910
    ApprovedInvestigational

    Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels.

    Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 19-Nor-1alpha,25-dihydroxyvitamin D2
  6. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. … As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsSynonyms: N,N'-((2-AMINO-4,6-DIMETHYL-3-OXO-3H-PHENOXAZINE-1,9-DIYL)-BIS(CARBONYLIMINO(2-HYDROXYPROPYLIDENE)CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE, Actinomycin D
  7. Drug

    Golcadomide

    go.drugbank.com/drugs/DB18115
    Investigational

    Synonyms: 2-[(3S)-2,6-dioxopiperidin-3-yl]-4-{[(2-fluoro-4-{[3-(morpholin-4-yl)azetidin-1-yl]methyl} phenyl) methyl]amino}-1H-isoindole-1,3(2H)-dione
  8. Drug

    Vonlerolizumab

    go.drugbank.com/drugs/DB16352
    Investigational

    Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic

    Synonyms: Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody: .gamma.1 heavy chain (1-447), Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody
  9. Drug

    Ziltivekimab

    go.drugbank.com/drugs/DB18836
    Investigational

    Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).

    Synonyms: Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal 2e2.3a9.6a3 .gamma.1-chain), disulfide with human monoclonal 2e2.3a9.6a3 .kappa.
  10. Drug

    MK-4541

    go.drugbank.com/drugs/DB17016
    Experimental

    MK-4541 is a 4-azasteroid and a selective androgen receptor modulator (SARM). MK-4541 acts as a dual selective SARM and is both a potent androgen receptor antagonist and a 5α-reductase inhibitor.

    Synonyms: 2,2,2-trifluoroethyl N-[(1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,11a-trimethyl-7-oxo-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinolin-1-yl]carbamate