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Bardoxolone
go.drugbank.com/drugs/DB12651InvestigationalIt is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic
Xanthine
go.drugbank.com/drugs/DB02134InvestigationalIt is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine.
(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
go.drugbank.com/drugs/DB08553ExperimentalIt targets the protein serine/threonine-protein kinase B-raf.
1D-myo-inositol 1,4,5-trisphosphate
go.drugbank.com/drugs/DB03401ExperimentalInositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum.
Arsthinol
go.drugbank.com/drugs/DB08928ExperimentalIt has since been demonstrated that the agent possesses activity against amoebas and yaws.
Eperisone
go.drugbank.com/drugs/DB08992InvestigationalIt is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh.
5-methoxy-N,N-dimethyltryptamine
go.drugbank.com/drugs/DB14010IllicitInvestigationalIt is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad.
Calcimycin
go.drugbank.com/drugs/DB19408InvestigationalIt binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in rat liver mitochondria.
Enlonstobart
go.drugbank.com/drugs/DB21890Investigational[A274486] It targets the programmed cell death protein 1 (PD-1), is being developed by the CSPC Pharmaceutical Group for the treatment of advanced cervical cancer and other solid tumours.