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JAK4D
go.drugbank.com/drugs/DB18527ExperimentalJAK4D is a first-in-class thyrotropin-releasing hormone (TRH)-based compound.
Synonyms: 5-oxo-l-prolyl-l-asparaginyl-l-prolyl-d-tyrosyl-d-tryptophanamide, L-pyroglutamyl-l-asparaginyl-l-prolyl-d-tyrosyl-d-tryptophan amideLevacetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigationalLevacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine
Categories: P-glycoprotein inhibitorsSynonyms: (s)-2-acetamido-4-methylpentanoic acid, L-leucine, n-acetyl-Supinoxin
go.drugbank.com/drugs/DB19010InvestigationalSupinoxin is under investigation in clinical trial NCT02003092 (RX-5902 Treatment of Subjects With Triple Negative Breast Cancer).
Synonyms: 1-(3,5-dimethoxyphenyl)-4-((6-fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl) piperazine, 1-piperazinecarboxamide, 4-(3,5-dimethoxyphenyl)-n-(7-fluoro-3-methoxy-2-quinoxalinyl)-Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingLGD-2226
go.drugbank.com/drugs/DB08089ExperimentalAn androgen receptor modulator.
Synonyms: 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-oneCategories: Heterocyclic Compounds, 2-RingTefidsogene civaparvovec
go.drugbank.com/drugs/DB16789InvestigationalIt consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes
Synonyms: EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA), A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUSClopenthixol
go.drugbank.com/drugs/DB13841InvestigationalClopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
Categories: Heterocyclic Compounds, 3-RingSynonyms: 4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol, 4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanolJNJ-39758979
go.drugbank.com/drugs/DB18899InvestigationalJNJ-39758979 is under investigation in clinical trial NCT01480388 (A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-PYRIMIDINAMINE, 4-((3R)-3-AMINO-1-PYRROLIDINYL)-6-(1-METHYLETHYL)-L-alloisoleucine
go.drugbank.com/drugs/DB01739ExperimentalSynonyms: allo-L-isoleucine, (2S,3R)-2-amino-3-methylpentanoic acidGlyceryl monocaprylate
go.drugbank.com/drugs/DB19362ApprovedSynonyms: Sunsoft 700 p-2, Cremercoor gc 8Dapiclermin
go.drugbank.com/drugs/DB17979ExperimentalDapiclermin is a recombinant ciliary neurotrophic factor.
Synonyms: 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine), 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine)