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Displaying results 431 - 440 of 10000 in total
  1. Drug

    9-(N-methyl-L-isoleucine)-cyclosporin A

    go.drugbank.com/drugs/DB13068
    Investigational

    9-(N-methyl-L-isoleucine)-cyclosporin A (NIM811) has been used in trials studying the treatment of Chronic Hepatitis C Genotype-1 Relapse.

  2. Drug

    Colforsin

    go.drugbank.com/drugs/DB02587
    Investigational

    Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also...

    Synonyms: 7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  3. Drug

    Tubercidin

    go.drugbank.com/drugs/DB03172
    Experimental

    An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Sparsomycin A, 7-deazaadenosine
  4. Drug

    Meningococcal polysaccharide vaccine group W-135

    go.drugbank.com/drugs/DB13887
    ApprovedInvestigational

    *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.

    Mixtures: Menomune-A/c/y/w-135, Menomune-A/c/y/w-135Synonyms: Neisseria meningitidis group W-135 polysaccharide antigen, A, Meningococcal polysaccharide antigen group W-135
  5. Drug

    Venetoclax

    go.drugbank.com/drugs/DB11581
    ApprovedInvestigational

    Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. … A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who have received at least one

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide, 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
  6. Drug

    Nigericin

    go.drugbank.com/drugs/DB14056
    Experimental

    A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: Polyetherin A, Helixin C
  7. Drug

    Zoalene

    go.drugbank.com/drugs/DB11480
    ExperimentalVet approved

    Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.

    Synonyms: Coccidine A
  8. Drug

    Aspergillopepsin-2

    go.drugbank.com/drugs/DB16571
    Investigational

    Synonyms: Proctase-A, Aspergillopepsin-2
  9. Drug

    Octrizole

    go.drugbank.com/drugs/DB21133
    Experimental

    Octrizole is a small molecule drug. Octrizole has a monoisotopic molecular weight of 323.2 Da.

    Synonyms: Bisoctrizole related compound a
  10. Drug

    4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL

    go.drugbank.com/drugs/DB07087
    Experimental

    Synonyms: 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL