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Infliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab was first approved by the FDA in 1998 under the market name Remicade as an intravenous injection. … Inflectra, a first biosimilar drug product, was approved in 2016. In December 2017, Ixifi, a second biosimilar that was developed by Pfizer, was granted approval by the FDA.
Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERProducts: REMSIMA 100 MG, INFLECTRA 100 MGAvanafil
go.drugbank.com/drugs/DB06237ApprovedAvanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction.
Categories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 SubstratesSynonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamideIodine
go.drugbank.com/drugs/DB05382ApprovedInvestigationalIodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Mixtures: Prim - Royal P.M.T., Classic Swiss One 10 Multivitamin and Mineral TabProducts: BETAKON 100 ML GARGARA, NITIGRAF ® 350 MG/ML SOLUCION INYECTABLE.Levonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigational[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … It was initially granted FDA approval in 1982 and was the first emergency contraceptive containing only progesterone, showing high levels of efficacy and a lack of estrogenic adverse effects when compared
Synonyms: (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one, (-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-oneMixtures: MIRANOVA 100 MCG/20 MCG KAPLI TABLET, 21 ADET, FemSevenCombi 50 Mikrogramm/10 Mikrogramm/24 Stunden - Depot-PflasterCannabidiol
go.drugbank.com/drugs/DB09061ApprovedInvestigationalIt is approved for use as adjunctive treatment for symptomatic relief of spasticity in adult patients with multiple sclerosis (MS). … In contrast to THC's weak agonist activity, CBD has been shown to act as a negative allosteric modulator of the cannabinoid CB1 receptor, the most abundant G-Protein Coupled Receptor (GPCR) in the body
Mixtures: Dynabac 5.0Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AgonistsPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigational[A226608] Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines
Mixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Categories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 SubstratesKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: Ixoba M, Acunivive 90Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesAtracurium besylate
go.drugbank.com/drugs/DB00732ApprovedA non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate no...
Products: DEMATRAC 50 MG/5 ML İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPUL, Notrixum Injection 10 mg/mlOfloxacin
go.drugbank.com/drugs/DB01165ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acidOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: XENICAL 120 MG SERT JELATIN KAPSUL, 105 ADET, ORLISTAT 60 MG