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Doxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedHistamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: Safetussin PM, Safetussin PMProducts: Dg Health Sleep AidLevomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigationalMenthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-oc...
Mixtures: POMADA VILA, Sarna PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedRecently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].
Products: PRANEXXIN ® DUO 500 MG TABLETAS, PRANEXXIN DUO 2% POLVO PARA RECONSTITUIR ASUSPENSION ORAL.Sorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigationalSorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approve...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SORAFENIB DR. REDDYSTorasemide
go.drugbank.com/drugs/DB00214ApprovedInvestigationalTorasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: SUTRILNEO 5 MG COMPRIMIDOS DE LIBERACIÓN PROLONGADA, SUTRILNEO 10 MG COMPRIMIDOS DE LIBERACION PROLONGADACapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurr...
Mixtures: Reme D, Kapzin DCCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersPantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedOnly the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer.
Synonyms: D-pantothenic acidMixtures: VIL-Rx, Virt-PnPinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalPinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain...
International brands: Alevian DuoMixtures: DICETEL-DUO, DICETEL® DUOUlipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalUlipristal is currently recommended as first line therapy for emergency contraception, due to improved efficacy and similar side effect profile as compared to the traditional use of levonorgestrel or the … systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily debated due
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ACETATO DE ULIPRISTALBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states inclu...
Mixtures: BUFENCON INJECTION 5ML VIAL, BUFENCON INJECTION 5ML VIALCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates