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Icatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … [A4017,A263041] It was investigated as a potential treatment of hereditary angioedema (HAE) as bradykinin was implicated in HAE swelling; specifically, mice lacking B<sub>2</sub> receptors showed reduced
Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT EG, Icatibant STADA 30 mg Injektionslösung in einer FertigspritzeZinc oxide
go.drugbank.com/drugs/DB09321ApprovedInvestigationalZinc oxide is an inorganic compound used in a number of manufacturing processes. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments
Mixtures: Avon Anew Line Eliminator Neo-retinol Line Plumper SPF 15, Mineral Lip Tan Line SPF 30 Broad SpectrumCategories: Compounds used in a research, industrial, or household settingSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalSilodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder … neck, prostate, and prostatic urethra: the α<sub>1A</sub> subtype accounts for approximately 75% of α1-adrenoceptors in the prostate.
Categories: Drugs Used in Benign Prostatic HypertrophyProducts: SILODOSINA EG, SILODOSIN AL 4 MG HKPDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalThis block reduces the urgency to urinate and so it should not be used in people with urinary retention. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Products: DARUCIL® ER 15 MGIopamidol
go.drugbank.com/drugs/DB08947ApprovedInvestigationalIopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Categories: Compounds used in a research, industrial, or household settingProducts: PAMIRAY 370 ENJ. 50 ML 0,755 MG FLAKON, 1 ADET, PAMIRAY 370 ENJ. 100 ML 0,755 MG FLAKON, 1 ADETTrospium
go.drugbank.com/drugs/DB00209ApprovedInvestigationalTrospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. … [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination.
Products: Trospium Chloride ERGefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalGefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. … Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Synonyms: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamineProducts: GEFITINIB EGTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigational[L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher efficacy in reducing intraocular pressure and a reduced … It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension.
Mixtures: TRAVO/TIMOL AL 40UG/ML+5MG, TRAVO/TIMOL AL 40UG/ML+5MGProducts: TRAVOPROST EG, TRAVOPROST AL 40UG/MLAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: Osmolex ER, Osmolex ERCategories: Influenza A M2 Protein InhibitorFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigational[L40719] It has a number of therapeutic uses, including the management and prevention of infections and febrile neutropenia in patients receiving myelosuppressive chemotherapy or radiation therapy. … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.
Products: ZARZIO® 30 MU/0.5 ML SOLUCION INYECTABLE O PARA PERFUSION EN JERINGA PRECARGADA, IOR-LC