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Nifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigationalNifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine]. … [A190273] Nifedipine was granted FDA approval on 31 December 1981.[L11383]
Mixtures: NIF TEN 50Categories: Heterocyclic Compounds, 1-RingSodium bicarbonate
go.drugbank.com/drugs/DB01390ApprovedInvestigationalSodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Mixtures: PRONAT 500 mg+267 mg+160 mg/10 ml ORAL SÜSPANSIYON, 200 ML, GASVİN 500 MG + 267 MG + 160 MG / 10 ML SÜSPANSİYON, 200 MLProducts: NURSE BABY 50 MG/5 ML ORAL ÇÖZELTİ, 10 ADET, Sodium Bicarbonate 10 gr (650 mg)Pyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approvedAs its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. … It is also used in combination with [DB00366] (as the commercially available product Diclectin) for the treatment of nausea and vomiting in pregnancy.
Mixtures: LYSOBACT 20 MG/10 MG PASTİL, 30 ADET, PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 1-RingRamipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalRamipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of AC...
Mixtures: Trinomia 100 mg/20 mg/10 mg Hartkapseln, Trinomia 100 mg/20 mg/5 mg HartkapselnCategories: Heterocyclic Compounds, 2-RingBurosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalBurosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of rickets.
Categories: Fibroblast Growth Factor-23 Blocking AntibodiesProducts: CRYSVITA® SOLUTION FOR INJECTION 10 MG/ML, CRYSVITA 10 MG SOLUTION FOR INJECTIONSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin was granted FDA approval on October 16, 2006[L6061]. … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256
Mixtures: JANUMET 50 MG/500 MG FILM KAPLI TABLET, 56 ADET, JANUMET 50 MG/850 MG FILM KAPLI TABLET, 56 ADETCategories: Heterocyclic Compounds, 1-RingAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalIn vivo, abacavir sulfate dissociates to its free base, abacavir. … Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
Mixtures: TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,FILM KAPLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-RingIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalIron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
Mixtures: Bal-Care DHA, Bal-Care DHA EssentialProducts: VELTIFER 100 MG/5 ML ORAL ÇÖZELTİ, 10 ADET, VELTIFER 100 MG/5 ML ORAL ÇÖZELTİ, 20 ADETRofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%. … The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2.
Categories: Heterocyclic Compounds, 1-Ring, COX-2 InhibitorsSynonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanoneNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Categories: Heterocyclic Compounds, 1-RingSynonyms: N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine