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Fluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalHMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. … Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2B6 InducersProducts: Fluvastatin Sandoz 20 mg - Hartkapseln, LESCOL XL 80 MG TABLET, 28 ADETTuparstobart
go.drugbank.com/drugs/DB19118InvestigationalTuparstobart is under investigation in clinical trial NCT05287113 (Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-line Treatment in Participants With Pd-l1-positive (CPS
Synonyms: gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-46*02 (80.4%)-(IGHD) -IGHJ4*01 (100%), CDR-IMGT[8.8.14] (26-33.51-58.97-110)) (1-121)-Homo sapiens IGHG1*03, G1m3, nG1m1, G1v29 CH2 A84.4 (CH1, R120 (218) (122-219), hinge 1-15 (220-234), CH2 N8Zonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalThe US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … [L42530,L42535] Zonisamide represents an alternative for patients that remain refractory to established antiepileptic drugs. In 1989, it was approved for commercial use in Japan.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: ZONISAHEXAL 50 MG HKP, Zonibon 50 mg-HartkapselnBilastine
go.drugbank.com/drugs/DB11591ApprovedBilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Categories: Heterocyclic Compounds, 2-RingProducts: BILASTINA EG, BILAXTEN 20 MG TABLET ,10 TABLETFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnFlupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. … It is approved for use in Canada and other countries around the world, but not in the US.
Mixtures: DORMIR TABLET, 20 ADETCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsEscitalopram
go.drugbank.com/drugs/DB01175ApprovedInvestigational[A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. … [L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with some evidence suggesting
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: ESCITALOPRAM EG, ESCITALOPRAM EG STADA ITALIAMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigationalmanage pain in endometriosis, prevent pregnancy, and is also used in palliative care for endometrial and renal carcinoma. … [L8657,L8660,L8663,L8666,L8669] Medroxyprogesterone acetate was granted FDA approval on 18 June 1959.[L8657]
Synonyms: (6α)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione, 6α-Methyl-4-pregnene-3,20-dion-17α-ol acetateInternational brands: Depo-subq provera 104Mycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigationalit reaches the small intestine. … [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.[A249170].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesSynonyms: (e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acidMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersProducts: ALDOLAN 100 MG/2 ML AMPUL, 5 ADET, ALDINE 100 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 5 AMPULRupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalIt was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use. … Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: RUPATADINA EG, RUFTAN 10 MG TABLET, 20 ADET