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Displaying results 4421 - 4430 of 6951 in total
  1. Target

    Integrin beta-2

    go.drugbank.com/bio_entities/BE0001041
    TargetHumans

    Integrin ITGAM:ITGB2 is also a receptor for factor X. Integrin ITGAD:ITGB2 is a receptor for ICAM3 and VCAM1 (PubMed:10438935, PubMed:8777714, PubMed:9841932). … Integrin ITGAM:ITGB2/MAC-1 complex functions as a signaling receptor for the ligand receptor ICAM1, ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124).

    Synonyms: Complement receptor C3 subunit beta
  2. Target

    Sialic acid-binding Ig-like lectin 7

    go.drugbank.com/bio_entities/BE0001648
    TargetHumans

    In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through

    Synonyms: Adhesion inhibitory receptor molecule 1
  3. Drug

    Homatropine methylbromide

    go.drugbank.com/drugs/DB00725
    Approved

    Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics.

    Categories: Drugs for Functional Gastrointestinal Disorders
  4. Drug

    Diphemanil

    go.drugbank.com/drugs/DB13720
    ApprovedVet approvedWithdrawn

    Categories: Drugs for Functional Gastrointestinal Disorders
  5. Drug

    Fosravuconazole

    go.drugbank.com/drugs/DB15204
    Investigational

    Fosravuconazole is under investigation in clinical trial NCT03378661 (BENDITA BEnznidazole New Doses Improved Treatment and Associations).

    Categories: Antifungals for Systemic Use, Antifungals for Dermatological Use
  6. Drug

    Berotralstat

    go.drugbank.com/drugs/DB15982
    ApprovedInvestigational

    [L41960] In December 2025, the FDA expanded Berotralstat pediatric use with approval of an oral pellet formulation for prophylaxis in children with HAE aged 2 and older.[L54793,L54798]

  7. Target

    GTP-binding nuclear protein Ran

    go.drugbank.com/bio_entities/BE0004559
    TargetHumans

    GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed:10400640, PubMed:17209048, PubMed:26272610, PubMed:27306458, PubMed:8276887, PubMed:8636225, Pu...

    Synonyms: Androgen receptor-associated protein 24
  8. Drug

    Maxy-G34

    go.drugbank.com/drugs/DB05718
    Investigational

    It is being developed by Maxygen, Inc. for the treatment of chemotherapy-induced neutropenia.

  9. Drug

    ZKN-013

    go.drugbank.com/drugs/DB32582
    Experimental

    ZKN-013 is a readthrough inducer under investigation for rare dermatological diseases.[L56075]

  10. Drug

    Vixotrigine

    go.drugbank.com/drugs/DB11706
    Investigational

    Vixotrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.