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Displaying results 4431 - 4440 of 10000 in total
  1. Drug

    Amrubicin

    go.drugbank.com/drugs/DB06263
    Investigational

    In 2002, Amrubicin was approved and launched for sale in Japan based on Phase 2 efficacy data in both SCLC and NSCLC. … Amrubicin is a third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer. Pharmion licensed the rights to Amrubicin in November 2006.

  2. Drug

    Ferumoxsil

    go.drugbank.com/drugs/DB09507
    ApprovedWithdrawn

    Categories: Compounds used in a research, industrial, or household setting, Complex Mixtures
  3. Drug

    Alvocidib

    go.drugbank.com/drugs/DB03496
    Investigational

    Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. … It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.

  4. Drug

    Zimelidine

    go.drugbank.com/drugs/DB04832
    ApprovedWithdrawn

    Additionally, zimelidine was charged to cause an increase in suicidal ideation and/or attempts among depressive patients.

  5. Target

    Baculoviral IAP repeat-containing protein 2

    go.drugbank.com/bio_entities/BE0010675
    TargetHumans

    Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner.

    Synonyms: TNFR2-TRAF-signaling complex protein 2
  6. Drug

    Methamidophos

    go.drugbank.com/drugs/DB14972
    Experimental

    Leukemia in First Remission). … Methamidophos is under investigation in clinical trial NCT03223753 (Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Newly Diagnosed Acute Lymphoblastic

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Culex pipiens

    go.drugbank.com/drugs/DB14165
    Approved

    Culex pipiens allergenic extract is used in allergenic testing.

  8. Drug

    Sarocladium strictum

    go.drugbank.com/drugs/DB14168
    Approved

    Sarocladium strictum allergenic extract is used in allergenic testing.

  9. Drug

    CZEN 002

    go.drugbank.com/drugs/DB05479
    Experimental

    Studies attempting to understand the candidacidal activity of derivatives of alpha-MSH have focused on the alpha-MSH amino acid sequence (6-13), which contains the invariant core sequence His-Phe-Arg-Trp … It appears that CZEN-002 works on a receptor in yeast that has yet to be identified.

  10. Drug

    Leptin

    go.drugbank.com/drugs/DB05098
    Investigational

    Although leptin is a circulating signal that reduces appetite, in general, obese people have an unusually high circulating concentration of leptin. … Thus, obesity develops when people take in more energy than they use over a prolonged period of time, and this excess food intake is not driven by hunger signals, occurring in spite of the anti-appetite