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Displaying results 4441 - 4450 of 10000 in total
  1. Target

    Peroxiredoxin-2

    go.drugbank.com/bio_entities/BE0001972
    TargetHumans

    Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)

    Polypeptides: Peroxiredoxin-2Synonyms: Thioredoxin-dependent peroxiredoxin 2
  2. Target

    Synaptotagmin-2

    go.drugbank.com/bio_entities/BE0002138
    TargetHumans

    Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By ...

    Polypeptides: Synaptotagmin-2
  3. Target

    Stromelysin-2

    go.drugbank.com/bio_entities/BE0003689
    TargetHumans

    Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase

    Polypeptides: Stromelysin-2Synonyms: SL-2, Transin-2
  4. Target

    Profilin-2

    go.drugbank.com/bio_entities/BE0004295
    TargetHumans

    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG

    Polypeptides: Profilin-2
  5. Target

    Nucleobindin-2

    go.drugbank.com/bio_entities/BE0008701
    TargetHumans

    Calcium-binding protein which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G protein) alpha subunit GNA...

    Polypeptides: Nucleobindin-2
  6. Target

    Hexokinase-2

    go.drugbank.com/bio_entities/BE0009792
    TargetHumans

    Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:23185017, PubMed:26985301, PubMed:29298880). Mediates the initial s...

    Polypeptides: Hexokinase-2
  7. Target

    Semenogelin-2

    go.drugbank.com/bio_entities/BE0009916
    TargetHumans

    Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa

    Polypeptides: Semenogelin-2
  8. Target

    Cadherin-2

    go.drugbank.com/bio_entities/BE0012803
    TargetHumans

    Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regula...

    Polypeptides: Cadherin-2
  9. Target

    Dynamin-2

    go.drugbank.com/bio_entities/BE0013402
    TargetHumans

    Catalyzes the hydrolysis of GTP and utilizes this energy to mediate vesicle scission at plasma membrane during endocytosis and filament remodeling at many actin structures during organization of the actin cytoskeleton (PubMed:15731758, P...

    Polypeptides: Dynamin-2Synonyms: Dynamin 2
  10. Target

    Perilipin-2

    go.drugbank.com/bio_entities/BE0018750
    TargetHumans

    Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets

    Polypeptides: Perilipin-2