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Viper antivenom
go.drugbank.com/drugs/DB14114ApprovedInvestigationalANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation
MDX-1379
go.drugbank.com/drugs/DB05329InvestigationalMDX-1379 vaccine consists of two gp100 melanoma peptides. This drug is underinvestigation to treat malignant melanoma.
Xanthium strumarium pollen
go.drugbank.com/drugs/DB10356ApprovedXanthium strumarium pollen is the pollen of the Xanthium strumarium plant. Xanthium strumarium pollen is mainly used in allergenic testing.
Mixtures: Number Four Weed Mixture, Number Two Weed MixtureMupadolimab
go.drugbank.com/drugs/DB16488InvestigationalNCT04464395 and NCT04734873 assessed its use for hospitalized COVID-19 patients alone or with standard care. … CPI-006 was investigated in clinical trials NCT03454451, NCT04464395, and NCT04734873 to evaluate its safety and efficacy.
Categories: Experimental Unapproved Treatments for COVID-19Aranidipine
go.drugbank.com/drugs/DB09229ExperimentalAranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. … [A31895] It was developed by Maruko Seiyaku, introduced by Taiho and launched in Japan in 1997.[T88]
NP2
go.drugbank.com/drugs/DB06308InvestigationalNP2 is a replication defective HSV-1 based gene transfer vector engineered to express human preproenkephalin. … It was under investigation in clinical trial NCT01291901 (NP2 Enkephalin For Treatment of Intractable Cancer Pain).
Zunsemetinib
go.drugbank.com/drugs/DB16502InvestigationalAdditionally, ATI-450 was studied in a terminated trial (NCT05511519) to treat patients with psoriatic arthritis. … ATI-450 was under investigation in clinical trials (NCT05279417 and NCT05216224) for treating patients with rheumatoid arthritis and hidradenitis suppurativa, respectively.
Categories: Experimental Unapproved Treatments for COVID-19Citicoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnIt has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsEvofosfamide
go.drugbank.com/drugs/DB06091InvestigationalTH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. … TH-302 is a novel cancer therapeutic specifically activated under the low oxygen or "hypoxic" conditions typical of solid tumor cancer cells.
SLV319
go.drugbank.com/drugs/DB05077ExperimentalSLV319 belongs to a novel class of agents called CB1 antagonists, which work by blocking the cannabinoid type 1 (CB1) receptor. … It is developed for the treatment of obesity and other metabolic disorders.