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Tianeptine
go.drugbank.com/drugs/DB09289InvestigationalTianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946]. … Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) [A31983].
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSplicing factor 3B subunit 1
go.drugbank.com/bio_entities/BE0009359TargetHumansThe 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA … Also acts as a component of the minor spliceosome, which is involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077, PubMed:33509932).
Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunitATX-101
go.drugbank.com/drugs/DB05780InvestigationalATX-101 (medical), sodium deoxycholate for subcutaneous injection, is being evaluated as a treatment for the reduction of localized fat deposits. … As a naturally occurring component of the human body, deoxycholate is considered a ‘biocompatible’ detergent that solubilizes fat in the small intestine.
AGRO100
go.drugbank.com/drugs/DB04998InvestigationalPre-clinical testing demonstrates that the AGRO100 inhibition of nucleolin function produces anti-cancer effects against multiple types of the disease, including lung, prostate, breast, cervical, and colon … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.
Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10788ApprovedInvestigationalBordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) is a vaccine that contains inactivated acellular pertussis antigen that is isolated from Bordetella pertussis culture.
Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, 3 ANTIGENProducts: PERTAGEN® SUSPENSION FOR INJECTION 0.5 ML/DOSESerine/threonine-protein kinase PRP4 homolog
go.drugbank.com/bio_entities/BE0009527TargetHumansConnects chromatin mediated regulation of transcription and pre-mRNA splicing (PubMed:12077342). … Associates with U5 snRNP and NCOR1 deacetylase complexes which may allow a coordination of pre-mRNA splicing with chromatin remodeling events involved in transcriptional regulation (PubMed:12077342).
Synonyms: PRP4 pre-mRNA-processing factor 4 homologHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. … Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2.
Mixtures: Royal Whitening Pre-Brush, K-100Categories: Compounds used in a research, industrial, or household settingTG-100801
go.drugbank.com/drugs/DB05075InvestigationalTG100801 is a topically applied kinase inhibitor in macular degeneration patients.
Categories: Heterocyclic Compounds, 1-RingGFT14
go.drugbank.com/drugs/DB05061ExperimentalThe risks of medical interaction are weak and GFT14 may be easily combined with statins or other antidiabetic molecules (glitazones). … GFT14 is a new class of medicaction for treatment of cardiometabolic disease.
Human vaccinia virus immune globulin
go.drugbank.com/drugs/DB14112ApprovedInvestigationalHuman vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine … Most compounds used currently are intravenous formulations, which contain no preservatives - unlike prior intramuscular compounds which contained thiomersal, a mercury derivative preservative that could
Categories: Immunoglobulin G, Human Immunoglobulin G