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Displaying results 441 - 450 of 10000 in total
  1. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    cell types) that catalyze the synthesis of cyclic guanosine monophosphate (cGMP) in response to activation by nitric oxide (NO). … [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis and thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC

    Products: VERQUVO FILM-COATED TABLET 10MG, VERQUVO® 10MG TABLETAS RECUBIERTAS
  2. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).

    Synonyms: (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamineInternational brands: Animex-On
  3. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and

    Mixtures: DORZOLAMIDE AND TIMOLOL STADA EYE DROPS 20MG/5MG, Dorzolamide and TimololCategories: latanoprost and dorzolamide, Antiglaucoma Preparations and Miotics
  4. Drug

    Diazepam

    go.drugbank.com/drugs/DB00829
    ApprovedIllicitInvestigationalVet approved

    Its actions are mediated by enhancement of gamma-aminobutyric acid activity. … This current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy [L5200].

    Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: E Pam Tab 10mg, DIAZEPAM ABZ 10MG
  5. Drug

    Sitagliptin

    go.drugbank.com/drugs/DB01261
    ApprovedInvestigational

    Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].

    Mixtures: Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Alimentary Tract and Metabolism, metformin and sitagliptin
  6. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. … [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines.

    Synonyms: (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamideMixtures: Sumatriptan and Naproxen Sodium, Sumatriptan and Naproxen Sodium
  7. Drug

    Ambrosia confertiflora pollen

    go.drugbank.com/drugs/DB10872
    Approved

    Ambrosia confertiflora pollen is the pollen of the Ambrosia confertiflora plant. Ambrosia confertiflora pollen is mainly used in allergenic testing.

    Synonyms: weakleaf bur ragweed pollen extractCategories: Non-Standardized Pollen Allergenic Extract
  8. Drug

    Mycophenolic acid

    go.drugbank.com/drugs/DB01024
    ApprovedInvestigational

    [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity.

    Categories: Mycophenolic Acid and Prodrugs, Antineoplastic and Immunomodulating AgentsProducts: MOWEL 250MG FILMTABLETTEN, MYCOPHENOLAT 1A 250MG HART
  9. Drug

    Thiothixene

    go.drugbank.com/drugs/DB01623
    Approved

    A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

    Products: Navane Capsules 10mg, Navane Cap 2mg
  10. Drug

    Tenofovir alafenamide

    go.drugbank.com/drugs/DB09299
    ApprovedInvestigational

    [T239] Tenofovir alafenamide is an alanine ester form characterized for presenting low systemic levels but high intracellular concentration. … [L4388,L9010] Tenofovir alafenamide was developed by Gilead Sciences Inc and granted FDA approval on 5 November 2015.[L6271]

    Mixtures: BIKTARVY FILM-COATED TABLETS 50MG/200MG/25MG, ODEFSEY FILM-COATED TABLET 200MG/25MG/25MGCategories: Tenofovir and prodrugs, Amino Acids, Peptides, and Proteins