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Eftrenonacog alfa
go.drugbank.com/drugs/DB11608ApprovedIt is an X-linked genetic disease caused by mutation of the gene for coagulation protein factor IX (FIX), leading to decreased levels of endogenous factor IX and increased susceptibility to recurrent bleeding … Eftrenonacog alfa was developed and marketed as Alprolix for intravenous injection by Biogen. It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016.
Synonyms: Recombinant human coagulation factor IX, FC Fusion protein, Coagulation factor IX recombinant immunoglubulin g1 fusion proteinProducts: ALPROLIX® 250 UICalcium polycarbophil
go.drugbank.com/drugs/DB14684ApprovedLess gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. … is physiologically inert, and does not cause gastrointestinal irritation.
Categories: Compounds used in a research, industrial, or household settingProducts: Up and Up Fiber Therapy, FIBROSYL®Sugarcane
go.drugbank.com/drugs/DB10906ApprovedSugarcane allergenic extract is used in allergenic testing.
Products: Sugar CaneMethoxy polyethylene glycol-epoetin beta
go.drugbank.com/drugs/DB09107ApprovedInvestigationalESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia. … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.
Categories: Compounds used in a research, industrial, or household settingProducts: MIRCERA 100 UG/0.3ML, MIRCERA 120 UG/0.3MLPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalWhile its use has been approved in the early 1960's by the FDA [A32163], safety and effectiveness of pyrithione zinc has been reported for decades. … Pyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Synonyms: Pyridinethiol N-oxide, 2-pyridinethiol 1-oxideMixtures: Z-plus Shampoo, Solep Premier Hi GroNimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnNimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. … Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.
Mixtures: NIMOKAIN %1 + %5 JEL, 50 G, SULIDIN PLUS %1 + %5 LIKIT JEL, 30 GCategories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-SteroidalQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalIt is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. … An alkaloid derived from the bark of the cinchona tree.
Synonyms: (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol, (R)-(−)-quinineMixtures: IRUDERM 1Mannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalOn October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for … this indication under the name BRONCHITOL® by Chiesi USA Inc.
Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol ATolmetin
go.drugbank.com/drugs/DB00500ApprovedA non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Synonyms: 1-Methyl-5-p-toluoylpyrrole-2-acetic acid, 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acidCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingAspergillus oryzae
go.drugbank.com/drugs/DB10448ApprovedAspergillus oryzae allergenic extract is used in allergenic testing.
Products: Lactozyme - Cap