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Chloramphenicol
go.drugbank.com/drugs/DB00446ApprovedInvestigationalVet approvedWithdrawnAn antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically. … (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this
Synonyms: D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol, D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamideCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C19 InhibitorsNepidermin
go.drugbank.com/drugs/DB14145InvestigationalInternational brands: Kang He Su, Regen-DMixtures: EASYDEW DW EGF Derma Oneshot AmpouleCemiplimab
go.drugbank.com/drugs/DB14707ApprovedInvestigationalBy blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. … Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsSunitinib
go.drugbank.com/drugs/DB01268ApprovedInvestigationalFor these purposes, sunitinib is generally available as an orally administered formulation. Sunitinib inhibits cellular signaling by targeting multiple RTKs.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SUNITINIB DR. REDDY'STriclosan
go.drugbank.com/drugs/DB08604ApprovedAn aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Mixtures: Germa TanProducts: Kay QSR, PF Anti BacAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. … Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's.
Categories: Dopamine D2 Receptor Antagonists, P-glycoprotein inhibitorsProducts: DM-AR, ARIGEN 5MGSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalSerplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … Most recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953]
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsBendamustine
go.drugbank.com/drugs/DB06769ApprovedInvestigationalThrough this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: BEN SPAL-P® 25, BENDAMUSTINA DR. REDDY'SPropofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedPropofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia.
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: PROPOFOL-PF %1 200 MG/20 ML I.V. ENJEKSİYONLUK/İNFÜZYONLUK EMÜLSİYON, 5 ADETPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigationalPembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors