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Petrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalIt is used as an ointment base, topical protectant, and lubricant.
Mixtures: Elizabeth Arden Eight Hr Protectant Clear, Veradex-ECategories: Compounds used in a research, industrial, or household settingMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine was granted FDA approval in 1941.[L12114] … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol, (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diolProducts: Kadian ER, Arymo EREzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalthat NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings
Mixtures: EZETIMIBE E SIMVASTATINA EG, EZETIMIBE E SIMVASTATINA EGProducts: EZETIMIBE EGDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnIt is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. … Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability [A19259].
Products: Eu-Med 200 mg SchmerztablettenBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigationalin glaucoma. … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996.
Mixtures: BRIMONIDINA E TIMOLOLO EG, BRIMONIDINA E TIMOLOLO EGCategories: Sympathomimetics in Glaucoma TherapyPenpulimab
go.drugbank.com/drugs/DB16747ApprovedInvestigational[A273848] In order to further reduce the risk of toxicities and improve efficacy, penpulimab was designed with Fc mutations in order to eliminate Fc receptor and complement-mediated effector function, … The use of an IgG1 backbone - as opposed to an IgG4 backbone as is typical in other anti-PD-1 antibodies like [nivolumab] - is intended to reduce the risk of immune-related adverse events.
Theophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalA methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...
Mixtures: Theophylline in Dextrose, Theophylline in DextroseProducts: Theo ER, Apo-theo ERHepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigational[A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Products: VAQTA 50 E/1 ml Injektionssuspension in einer Fertigspritze, VAQTA K pro infantibus 25 E/0,5 ml Injektionssuspension in einer FertigspritzeDiclofenamide
go.drugbank.com/drugs/DB01144ApprovedA carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Lovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigationalclinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%. … [A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD.
Products: LOVASTATINA EG