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Brecanavir
go.drugbank.com/drugs/DB04887InvestigationalBrecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV. … In December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment of HIV. The decision was based on issues regarding the formulation of the drug.
Dimethyl sulfone
go.drugbank.com/drugs/DB14090InvestigationalMixtures: Conart-MSM Sachet for Oral Solution, Condrosa-MSM Sachet for Oral SolutionInsulin beef
go.drugbank.com/drugs/DB09456ApprovedInsulin beef has been discontinued in the US and Canada since 2017.
Categories: Insulins and Analogues for Injection, Fast-ActingClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[A256718] Clozapine was approved by the FDA in 1989 for treatment-resistant schizophrenia under the brand CLOZARIL.
NasoVAX
go.drugbank.com/drugs/DB15859InvestigationalCreated by Altimmune, Inc., NasoVAX is currently being developed for seasonal and pandemic use as it can activate humoral and cellular immune responses. … As of June 2020, NasoVAX is being evaluated in a Phase 2 clinical trial for safety and effectivness in preventing worsening symptoms in hospitalized COVID-19 patients (NCT04442230).
EVT 201
go.drugbank.com/drugs/DB05721InvestigationalEVT 201 is a novel partial positive allosteric modulator of the GABAA receptor complex which is being developed as a treatment for insomnia. It is being developed by Evotec Inc.
Metolazone
go.drugbank.com/drugs/DB00524ApprovedInvestigationalA quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Categories: Antihypertensive Agents Indicated for HypertensionUDP-alpha-D-glucuronic acid
go.drugbank.com/drugs/DB03041ExperimentalA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. … In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. [PubChem]
Pranlukast
go.drugbank.com/drugs/DB01411InvestigationalIt antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Categories: Drugs for Obstructive Airway DiseasesR1295
go.drugbank.com/drugs/DB05122ExperimentalR1295 is an integrin antagonist currently in clinical trials for the treatment of rheumatoid arthritis.