Search

Displaying results 4511 - 4520 of 10000 in total
  1. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.

    Synonyms: Human t-PA (residues 1-3 and 176-527)
  2. Drug

    Resveratrol

    go.drugbank.com/drugs/DB02709
    Investigational

    The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet irradiation. In a 2004 issue of Science, Dr. … It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers.

    Synonyms: (E)-resveratrol, (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol
  3. Drug

    Stanozolol

    go.drugbank.com/drugs/DB06718
    ApprovedVet approved

    Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes.

  4. Target

    Integrin alpha-X

    go.drugbank.com/bio_entities/BE0009967
    TargetHumans

    Functions as a receptor of the erythrocyte-specific adhesion molecule ICAM4 and mediates erythrophagocytosis (PubMed:16985175) … Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses.

    Synonyms: Leukocyte adhesion receptor p150,95
  5. Drug

    Ciluprevir

    go.drugbank.com/drugs/DB05868
    Investigational

    The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.

  6. Drug

    OSI-7836

    go.drugbank.com/drugs/DB05837
    Experimental

    The anti-tumor activity of OSI-7836 appeares to be less schedule dependent than gemcitabine. … This drug shows no unexpected toxicities; those observed appeared to be similar to other nucleoside agents.

  7. Drug

    TA-NIC

    go.drugbank.com/drugs/DB05445
    Investigational

    It is designed to raise anti-nicotine antibodies which bind to nicotine molecules in the patient's blood stream, reducing the rate and quantity of nicotine entry into the brain, to reduce the addictive … TA-NIC is a novel and proprietary vaccine in development as an aid to quitting smoking in motivated patients.

    Synonyms: TA-NIC
  8. Drug

    Etanautine

    go.drugbank.com/drugs/DB13636
    Experimental

    Categories: Ethers, Chemically Close to Antihistamines
  9. Drug

    Chloride ion

    go.drugbank.com/drugs/DB14547
    Investigational

    Mixtures: PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1000 ML, PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1500 ML
  10. Drug

    Amifostine

    go.drugbank.com/drugs/DB01143
    ApprovedInvestigational

    A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.