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Flunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalFlunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and periphe...
Products: NATIL N 5MG, NATIL N 10MGPentolinium
go.drugbank.com/drugs/DB01090ApprovedPentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
IDD-1
go.drugbank.com/drugs/DB05439ExperimentalLipids promote the fusion of liposomes to cells. … As with other monoclonal antibodies, this process stimulates an immune response to a particular disease-related antigen.
SP1049C
go.drugbank.com/drugs/DB04978ExperimentalPreliminary data, in its first clinically tested indication, shows that SP1049C is active in Stage IV non-resectable adenocarcinoma of the esophagus. … [A260416] It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review.
Josamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
ICG-136
go.drugbank.com/drugs/DB17343ExperimentalICG-136 is a compound chimeric antigen receptor (cCAR) T-cell therapy developed by iCell Gene Therapeutics. It was investigated for the treatment of acute myeloid leukemia.
LuLym-T
go.drugbank.com/drugs/DB17405ExperimentalDeveloped by Lukas Biomedical, Inc., it is currently being investigated in hepatocellular carcinoma.
Mozafancogene autotemcel
go.drugbank.com/drugs/DB17723InvestigationalRP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
CMLVAX100
go.drugbank.com/drugs/DB05164ExperimentalIt is developed by Breakthrough Therapeutics and has completed phase I of its clinical trial.
ETC-588
go.drugbank.com/drugs/DB05456ExperimentalIt is believed that the removal of cholesterol by ETC-588 through this pathway may result in the reversal of atherosclerosis. … LUV are capable of transporting excess cholesterol from the vasculature to the liver for eventual elimination as part of the reverse lipid transport (RLT) pathway.