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Pomaglumetad methionil
go.drugbank.com/drugs/DB05096InvestigationalLY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039. … LY2140023 is an investigational drug from Lilly, which is being developed as a new treatment option for schizophrenia.
Categories: Amino Acids, Peptides, and ProteinsXanomeline
go.drugbank.com/drugs/DB15357ApprovedInvestigational[A264514] Xanomeline is a muscarinic agonist that was approved for the treatment of schizophrenia by the FDA in September 2024, becoming the first approved treatment for schizophrenia to target muscarinic … discovered that M1 and M4 muscarinic acetylcholine receptors are highly expressed in brain regions that are implicated in cognition.
Glutethimide
go.drugbank.com/drugs/DB01437ApprovedIllicitGlutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.
Categories: Hypnotics and SedativesStem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalThese exosomes can also consist of VEGF and matrix metalloproteinase-9 (MMP-9) which aid in angiogenesis and tissue repair. … Once secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites.
Glucagon
go.drugbank.com/drugs/DB00040ApprovedInvestigationalGlucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia. … [L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.
Categories: Sex Hormones and Insulins, Amino Acids, Peptides, and ProteinsProducts: GlucaGen 1 mg/ml - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, GlucaGen HypoKit 1 mg/ml - Pulver und Lösungsmittel zur Herstellung einer InjektionslösungSerelaxin
go.drugbank.com/drugs/DB05794Investigationalbones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy. … Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic
Categories: Vasodilators Used in Cardiac DiseasesMetrizoic acid
go.drugbank.com/drugs/DB09346ApprovedIn general, the drug was well tolerated by patients during cardiac examinations [A32091]. … Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA.
Categories: Compounds used in a research, industrial, or household settingLetterer-Siwe disease
go.drugbank.com/conditions/DBCOND0021755Drugs: VinblastineSynonyms: Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis, (Non-Hodgkin's lymphoma) or (histiocytosis X) or (Letterer-Siwe disease) or (lymphatic tissue Ca NOS)Cabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigational[L31198] While previously administered once monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].
Products: Apretude 30mg Film-Coated Tablet, Apretude 600mg Prolonged-release suspension for injectionBisoxatin
go.drugbank.com/drugs/DB09219ApprovedBisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine [L926]. … It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures.
Categories: Alimentary Tract and Metabolism