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Gridegalutamide
go.drugbank.com/drugs/DB21593InvestigationalGridegalutamide has a monoisotopic molecular weight of 818.32 Da.
Docirbrutinib
go.drugbank.com/drugs/DB21606InvestigationalDocirbrutinib has a monoisotopic molecular weight of 578.24 Da.
Tamuzimod
go.drugbank.com/drugs/DB21621InvestigationalTamuzimod has a monoisotopic molecular weight of 545.0 Da.
Lomedeucitinib
go.drugbank.com/drugs/DB21649InvestigationalLomedeucitinib has a monoisotopic molecular weight of 419.15 Da.
Bimokalner
go.drugbank.com/drugs/DB21717InvestigationalBimokalner has a monoisotopic molecular weight of 355.1 Da.
Ocadusertib
go.drugbank.com/drugs/DB21732InvestigationalOcadusertib has a monoisotopic molecular weight of 459.19 Da.
Mefloquine
go.drugbank.com/drugs/DB00358Approved[A226838] This drug has been the subject of widespread controversy due to concerns regarding neurotoxic effects; product information warns of potential serious neuropsychiatric effects.[A226838,L8953]
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (DL-ERYTHRO-.ALPHA.-2-PIPERIDYL-2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINEMETHANOLChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnDue to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 1-(p-chlorobenzenesulfonyl)-3-propylurea, 1-(p-chlorophenylsulfonyl)-3-propylureaDroxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalThe racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension.
Elacridar
go.drugbank.com/drugs/DB04881InvestigationalIn many cases, the appearance of multidrug resistance in cancer is due to a change in expression of protein inhibitors. As of August 2007 elacridar was not listed on GSK's product pipeline.
Categories: P-glycoprotein inhibitors